Cartilage matrix glycoprotein as a possible marker of osteoarthritis.

Research output: Contribution to journalArticle

Abstract

Subunits of a disulfide bonded 550,000 Da cartilage matrix glycoprotein have been detected in the serum of dogs with osteoarthritis (OA) produced by anterior cruciate ligament transection of one hind limb. Cartilage matrix glycoprotein also can be detected in synovial fluid from humans with OA but not in fluid from individuals with other joint diseases. However, in studies of serum from patients with arthroscopically proven focal OA associated with trauma, the presence or absence of cartilage matrix glycoprotein in serum, as detected by a qualitative immunolocation assay, does not correlate with the state of the cartilage.

Original languageEnglish
Pages (from-to)30-31
Number of pages2
JournalThe Journal of rheumatology. Supplement
Volume27
StatePublished - Feb 1991

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Matrilin Proteins
Osteoarthritis
Serum
Joint Diseases
Anterior Cruciate Ligament
Synovial Fluid
Disulfides
Cartilage
Extremities
Dogs
Wounds and Injuries

ASJC Scopus subject areas

  • Medicine(all)
  • Immunology
  • Rheumatology

Cite this

Cartilage matrix glycoprotein as a possible marker of osteoarthritis. / Fife, Rose.

In: The Journal of rheumatology. Supplement, Vol. 27, 02.1991, p. 30-31.

Research output: Contribution to journalArticle

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