Case-control comparison of quality of life in long-term ovarian germ cell tumor survivors

A gynecologic oncology group study

Patrick Monahan, Victoria Champion, Qianqian Zhao, Anna M. Miller, David Gershenson, Stephen D. Williams, David Cella

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Ovarian germ cell cancer is a rare tumor. Approximately 1000 to 2000 women in the United States will be diagnosed with ovarian germ cell cancer in 2007. When it occurs, it is usually diagnosed before age 20 and is highly responsive to therapy. Most patients live a full life span. The 5-year relative survival rate is 95%. This article describes differences in quality of life issues between ovarian germ cell cancer survivors and young women who have not experienced cancer and were matched to survivors on age, education, and race (by the acquaintance control method). Survivors and controls completed mail and phone surveys. A multivariable logistic regression model was adjusted for age, education, household income, marital status, and perception of fertility. Compared to controls, germ cell cancer survivors expressed more reproductive concerns and reported worse sexual functioning, but they also experienced greater appreciation of life and more affective (i.e., emotional) social support. Future research is suggested to test interventions to enhance quality of life for ovarian germ cell cancer survivors in the areas of sexual functioning and reproductive concerns, but only for survivors who are in distress or in need of the support. Potential screening questions are offered for clinicians, but further research is needed to assess their validity as screening tools.

Original languageEnglish
Pages (from-to)19-42
Number of pages24
JournalJournal of Psychosocial Oncology
Volume26
Issue number3
DOIs
StatePublished - Jun 16 2008

Fingerprint

Germ Cell and Embryonal Neoplasms
Survivors
Quality of Life
Logistic Models
Education
Marital Status
Postal Service
Social Support
Fertility
Neoplasms
Survival Rate
Ovarian Germ Cell Cancer
Research

Keywords

  • Case-control
  • Long-term cancer survivors
  • Ovarian germ cell cancer
  • Quality of life

ASJC Scopus subject areas

  • Applied Psychology
  • Oncology
  • Psychiatry and Mental health

Cite this

Case-control comparison of quality of life in long-term ovarian germ cell tumor survivors : A gynecologic oncology group study. / Monahan, Patrick; Champion, Victoria; Zhao, Qianqian; Miller, Anna M.; Gershenson, David; Williams, Stephen D.; Cella, David.

In: Journal of Psychosocial Oncology, Vol. 26, No. 3, 16.06.2008, p. 19-42.

Research output: Contribution to journalArticle

Monahan, Patrick ; Champion, Victoria ; Zhao, Qianqian ; Miller, Anna M. ; Gershenson, David ; Williams, Stephen D. ; Cella, David. / Case-control comparison of quality of life in long-term ovarian germ cell tumor survivors : A gynecologic oncology group study. In: Journal of Psychosocial Oncology. 2008 ; Vol. 26, No. 3. pp. 19-42.
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