Catheter ablation of ventricular tachycardia using radiofrequency techniques in patients without structural heart disease

L. S. Klein, W. M. Miles, F. K. Hackett, D. P. Zipes

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

It has been previously demonstrated that radiofrequency (RF) energy can be safely applied to successfully eliminate accessory pathways in patients with the Wolff-Parkinson White syndrome. This technique may also be used to successfully eliminate atrioventricular (AV) nodal reentrant tachycardia by elimination of either the fast or slow AV nodal pathways. However, RF energy has achieved only limited success in eliminating ventricular tachycardia (VT) in patients with structural heart disease, such as coronary artery disease and dilated cardiomyopathy. Direct-current catheter techniques have successfully eliminated VT in patients with and without structural heart disease, but this technique is limited by the risk of barotrauma and proarrhythmia. We used RF catheter ablation techniques to eliminate VT in patients without structural heart disease. Our results form the basis of this report. 16 patients (nine women and seven men; mean age 38; range 18 to 55 years) who did not have any identifiable structural heart disease by echocardiography where included in this study. These patients underwent RF catheter ablation to eliminate VT. Two patients had presented with syncope, nine with presyncope and five with palpitations only. The mean duration of symptoms was 6.7 years (range 0.5 to 20 years). VT was successfully eliminated by RF catheter techniques in 15 of the 16 patients (a 94% success rate). Importantly, successful ablation sites included regions other than the right ventricular outflow tract. Areas of VT origin therefore included the high right ventricular outflow tract (twelve patients), right ventricular septum near the tricuspid valve (three patients), and the lert ventricular septum (one patient). The only ablation failure was in a patient whose VT arose from a region near the His bundle. Successful ablation occurred in patients in whom an accurate pace map could be obtained and early local endocardial activation was obtainable. Further, firm catheter contact with endocardium was required for successful elimination of VT. RF ablation did not cause any identifiable arrhythmia and produced a minimal cardiac enzyme rise. It also resulted in no detectable change in cardiac function by Doppler echocardiography. Based on these findings, we conclude that RF catheter ablation of VT in patients without structural heart disease was highly effective and safe. It may therefore be considered as early therapy in these patients.

Original languageEnglish
Pages (from-to)179-189
Number of pages11
JournalHerz
Volume17
Issue number3
StatePublished - 1992

Fingerprint

Catheter Ablation
Ventricular Tachycardia
Heart Diseases
Ventricular Septum
Catheters
Syncope
Atrioventricular Nodal Reentry Tachycardia
Ablation Techniques
Barotrauma
Bundle of His
Endocardium
Wolff-Parkinson-White Syndrome
Tricuspid Valve
Doppler Echocardiography
Dilated Cardiomyopathy
Patient Rights
Secondary Prevention
Echocardiography
Cardiac Arrhythmias
Coronary Artery Disease

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Klein, L. S., Miles, W. M., Hackett, F. K., & Zipes, D. P. (1992). Catheter ablation of ventricular tachycardia using radiofrequency techniques in patients without structural heart disease. Herz, 17(3), 179-189.

Catheter ablation of ventricular tachycardia using radiofrequency techniques in patients without structural heart disease. / Klein, L. S.; Miles, W. M.; Hackett, F. K.; Zipes, D. P.

In: Herz, Vol. 17, No. 3, 1992, p. 179-189.

Research output: Contribution to journalArticle

Klein, LS, Miles, WM, Hackett, FK & Zipes, DP 1992, 'Catheter ablation of ventricular tachycardia using radiofrequency techniques in patients without structural heart disease', Herz, vol. 17, no. 3, pp. 179-189.
Klein, L. S. ; Miles, W. M. ; Hackett, F. K. ; Zipes, D. P. / Catheter ablation of ventricular tachycardia using radiofrequency techniques in patients without structural heart disease. In: Herz. 1992 ; Vol. 17, No. 3. pp. 179-189.
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