Cavitation detection during shock-wave lithotripsy

Michael R. Bailey, Yuri A. Pishchalnikov, Oleg A. Sapozhnikov, Robin O. Cleveland, James A. McAteer, Nathan A. Miller, Irina V. Pishchalnikova, Bret A. Connors, Lawrence A. Crum, Andrew P. Evan

Research output: Contribution to journalArticlepeer-review

72 Scopus citations


A system was built to detect cavitation in pig kidney during shock-wave lithotripsy (SWL) with a Dornier HM3 lithotripter. Active detection using echo on B-mode ultrasound, and passive cavitation detection using coincident signals on confocal orthogonal receivers, were used to interrogate the renal collecting system (urine) and the kidney parenchyma (tissue). Cavitation was detected in urine immediately upon shock-wave (SW) administration in urine or urine plus X-ray contrast agent but, in native tissue, cavitation required hundreds of SWs to initiate. Localization of cavitation was confirmed by fluoroscopy, sonography and by thermally marking the kidney using the passive cavitation detection receivers as high-intensity focused ultrasound sources. Cavitation collapse times in tissue and native urine were about the same, but less than in urine after injection of X-ray contrast agent. The finding that cavitation occurs in kidney tissue is a critical step toward determining the mechanisms of tissue injury in SWL.

Original languageEnglish (US)
Pages (from-to)1245-1256
Number of pages12
JournalUltrasound in Medicine and Biology
Issue number9
StatePublished - Sep 1 2005


  • Cavitation
  • Lithotripsy
  • Shock wave
  • Ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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