Celiac sprue in Down's syndrome

Considerations on a pathogenetic link

Thomas Nowak, F. K. Ghishan, K. Schulze Delrieu

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The association of celiac disease with Down's syndrome is described in two patients who presented with features of the malabsorption syndrome. The diagnosis was readily made by peroral jejunal mucosal biopsy. Both patients responded clinically to dietary gluten withdrawal and one patient demonstrated a recrudescence of symptoms and reappearance of jejunal mucosal atrophy upon rechallenge with dietary gluten. Genetic considerations in the etiology of both disorders are discussed.

Original languageEnglish (US)
Pages (from-to)280-283
Number of pages4
JournalAmerican Journal of Gastroenterology
Volume78
Issue number5
StatePublished - 1983
Externally publishedYes

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Celiac Disease
Down Syndrome
Glutens
Malabsorption Syndromes
Atrophy
Biopsy
Recurrence

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Celiac sprue in Down's syndrome : Considerations on a pathogenetic link. / Nowak, Thomas; Ghishan, F. K.; Schulze Delrieu, K.

In: American Journal of Gastroenterology, Vol. 78, No. 5, 1983, p. 280-283.

Research output: Contribution to journalArticle

Nowak, Thomas ; Ghishan, F. K. ; Schulze Delrieu, K. / Celiac sprue in Down's syndrome : Considerations on a pathogenetic link. In: American Journal of Gastroenterology. 1983 ; Vol. 78, No. 5. pp. 280-283.
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