Central nervous system and musculoskeletal medication profile of a veteran cohort with blast-related injuries

Dustin D. French, Matthew J. Bair, Elizabeth Bass, Robert R. Campbell, Kris Siddharthan

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Little is known about the utilization of central nervous system (CNS) and musculoskeletal (MS) medications in Operation Iraqi Freedom/Operation Enduring Freedom (OIF/ OEF) veterans with blast-related injuries (BRIs). We followed prescription drug use among a cohort of 133 OIF/OEF veterans with BRIs by using the Joint Theatre Trauma Registry, the Tampa Polytrauma Registry, and electronic medical records. We extracted 12 months of national medication records from the Veterans Health Administration Decision Support System and analyzed them with descriptive statistics. Over the 12-month period (fiscal year 2007), CNS medications comprised 27.9% (4,225/15,143) of total prescriptions dispensed to 90.2% (120/ 133) of our cohort. Approximately one-half (48.9%) of the 133 patients were treated with opioid analgesics. Nearly 60% received antidepressants. More than one-half (51.1%) of patients were treated with anticonvulsants. Benzodiazepines and antipsychotics were dispensed to 17.3% and 15.8%, respectively. For MS medicines, 804 were prescribed for 48.1% (64/ 133) of veterans. Nearly one-fourth (24.8%) were treated with skeletal muscle relaxants. The CNS and MS medications, in general, were continuously prescribed over the 12-month study period. This study provides insight into the complex medical management involved in the care of veterans with BRIs.

Original languageEnglish (US)
Pages (from-to)463-468
Number of pages6
JournalJournal of Rehabilitation Research and Development
Volume46
Issue number4
DOIs
StatePublished - Sep 24 2009

Fingerprint

Blast Injuries
Veterans
Central Nervous System
2003-2011 Iraq War
Registries
Afghan Campaign 2001-
Neuromuscular Agents
Veterans Health
United States Department of Veterans Affairs
Prescription Drugs
Electronic Health Records
Multiple Trauma
Benzodiazepines
Anticonvulsants
Opioid Analgesics
Antidepressive Agents
Antipsychotic Agents
Prescriptions
Joints
Wounds and Injuries

Keywords

  • Blast injuries
  • Central nervous system
  • Medications
  • Musculoskeletal
  • OIF/OEF
  • Opioids
  • Polytrauma
  • Prescription drug use
  • Rehabilitation
  • Veterans

ASJC Scopus subject areas

  • Rehabilitation

Cite this

Central nervous system and musculoskeletal medication profile of a veteran cohort with blast-related injuries. / French, Dustin D.; Bair, Matthew J.; Bass, Elizabeth; Campbell, Robert R.; Siddharthan, Kris.

In: Journal of Rehabilitation Research and Development, Vol. 46, No. 4, 24.09.2009, p. 463-468.

Research output: Contribution to journalArticle

French, Dustin D. ; Bair, Matthew J. ; Bass, Elizabeth ; Campbell, Robert R. ; Siddharthan, Kris. / Central nervous system and musculoskeletal medication profile of a veteran cohort with blast-related injuries. In: Journal of Rehabilitation Research and Development. 2009 ; Vol. 46, No. 4. pp. 463-468.
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