Centration of donor trephination in human corneal transplantation

Arun Brahma, Alan Ridgway, Andrew Tullo, Michael Boulton, Grenham Ireland, Stephen Bagley, Louise Carrington

Research output: Contribution to journalArticle

1 Scopus citations


Purpose. To develop and evaluate a new method to quantify centration of the trephined donor cornea relative to the limbus. Methods. After human donor corneas were trephined for penetrating keratoplasty, the remaining corneoscleral discs were stained and subjected to image analysis. The centration of the excised donor cornea relative to the limbus was calculated by measuring their centroids from the 'captured' images. Results. Fifty-two corneoscleral discs were analyzed. The average deviation from the centre was 0.32 mm (SD, 0.18 mm). Neither surgeon nor the type of trephine significantly influenced the mean centroid deviation. Conclusion. We have developed and evaluated a method to quantify centration of human donor cornea. In a small series, decentration did not correlate significantly with either the surgeon or the trephine.

Original languageEnglish (US)
Pages (from-to)325-328
Number of pages4
Issue number3
StatePublished - May 2000
Externally publishedYes


  • Decentration
  • Penetrating keratoplasty
  • Trephination

ASJC Scopus subject areas

  • Ophthalmology

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