Cerebrospinal fluid (1,3)-β-d-glucan detection as an aid for diagnosis of iatrogenic fungal meningitis

Jennifer L. Lyons, Karen Roos, Kieren A. Marr, Henry Neumann, Julie B. Trivedi, Dorlan J. Kimbrough, Lisa Steiner, Kiran T. Thakur, Daniel M. Harrison, Sean X. Zhang

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

This case series highlights our experience with use of the Fungitell assay for quantifying (1,3)-β-D-glucan in cerebrospinal fluid during the current U.S. outbreak of fungal meningitis related to contaminated methylprednisolone acetate. This test may prove a useful adjunct in diagnosis and management of exposed patients.

Original languageEnglish (US)
Pages (from-to)1285-1287
Number of pages3
JournalJournal of Clinical Microbiology
Volume51
Issue number4
DOIs
StatePublished - Apr 2013
Externally publishedYes

Fingerprint

Fungal Meningitis
Glucans
Disease Outbreaks
Cerebrospinal Fluid
methylprednisolone acetate
polyglucosan

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Lyons, J. L., Roos, K., Marr, K. A., Neumann, H., Trivedi, J. B., Kimbrough, D. J., ... Zhang, S. X. (2013). Cerebrospinal fluid (1,3)-β-d-glucan detection as an aid for diagnosis of iatrogenic fungal meningitis. Journal of Clinical Microbiology, 51(4), 1285-1287. https://doi.org/10.1128/JCM.00061-13

Cerebrospinal fluid (1,3)-β-d-glucan detection as an aid for diagnosis of iatrogenic fungal meningitis. / Lyons, Jennifer L.; Roos, Karen; Marr, Kieren A.; Neumann, Henry; Trivedi, Julie B.; Kimbrough, Dorlan J.; Steiner, Lisa; Thakur, Kiran T.; Harrison, Daniel M.; Zhang, Sean X.

In: Journal of Clinical Microbiology, Vol. 51, No. 4, 04.2013, p. 1285-1287.

Research output: Contribution to journalArticle

Lyons, JL, Roos, K, Marr, KA, Neumann, H, Trivedi, JB, Kimbrough, DJ, Steiner, L, Thakur, KT, Harrison, DM & Zhang, SX 2013, 'Cerebrospinal fluid (1,3)-β-d-glucan detection as an aid for diagnosis of iatrogenic fungal meningitis', Journal of Clinical Microbiology, vol. 51, no. 4, pp. 1285-1287. https://doi.org/10.1128/JCM.00061-13
Lyons, Jennifer L. ; Roos, Karen ; Marr, Kieren A. ; Neumann, Henry ; Trivedi, Julie B. ; Kimbrough, Dorlan J. ; Steiner, Lisa ; Thakur, Kiran T. ; Harrison, Daniel M. ; Zhang, Sean X. / Cerebrospinal fluid (1,3)-β-d-glucan detection as an aid for diagnosis of iatrogenic fungal meningitis. In: Journal of Clinical Microbiology. 2013 ; Vol. 51, No. 4. pp. 1285-1287.
@article{eca1a8b1f34d43bfa6c63499fd044ae3,
title = "Cerebrospinal fluid (1,3)-β-d-glucan detection as an aid for diagnosis of iatrogenic fungal meningitis",
abstract = "This case series highlights our experience with use of the Fungitell assay for quantifying (1,3)-β-D-glucan in cerebrospinal fluid during the current U.S. outbreak of fungal meningitis related to contaminated methylprednisolone acetate. This test may prove a useful adjunct in diagnosis and management of exposed patients.",
author = "Lyons, {Jennifer L.} and Karen Roos and Marr, {Kieren A.} and Henry Neumann and Trivedi, {Julie B.} and Kimbrough, {Dorlan J.} and Lisa Steiner and Thakur, {Kiran T.} and Harrison, {Daniel M.} and Zhang, {Sean X.}",
year = "2013",
month = "4",
doi = "10.1128/JCM.00061-13",
language = "English (US)",
volume = "51",
pages = "1285--1287",
journal = "Journal of Clinical Microbiology",
issn = "0095-1137",
publisher = "American Society for Microbiology",
number = "4",

}

TY - JOUR

T1 - Cerebrospinal fluid (1,3)-β-d-glucan detection as an aid for diagnosis of iatrogenic fungal meningitis

AU - Lyons, Jennifer L.

AU - Roos, Karen

AU - Marr, Kieren A.

AU - Neumann, Henry

AU - Trivedi, Julie B.

AU - Kimbrough, Dorlan J.

AU - Steiner, Lisa

AU - Thakur, Kiran T.

AU - Harrison, Daniel M.

AU - Zhang, Sean X.

PY - 2013/4

Y1 - 2013/4

N2 - This case series highlights our experience with use of the Fungitell assay for quantifying (1,3)-β-D-glucan in cerebrospinal fluid during the current U.S. outbreak of fungal meningitis related to contaminated methylprednisolone acetate. This test may prove a useful adjunct in diagnosis and management of exposed patients.

AB - This case series highlights our experience with use of the Fungitell assay for quantifying (1,3)-β-D-glucan in cerebrospinal fluid during the current U.S. outbreak of fungal meningitis related to contaminated methylprednisolone acetate. This test may prove a useful adjunct in diagnosis and management of exposed patients.

UR - http://www.scopus.com/inward/record.url?scp=84875862239&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84875862239&partnerID=8YFLogxK

U2 - 10.1128/JCM.00061-13

DO - 10.1128/JCM.00061-13

M3 - Article

VL - 51

SP - 1285

EP - 1287

JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

SN - 0095-1137

IS - 4

ER -