Characterization of aleutian mink disease virus

Ji Won Yoon, A. Dunker, A. J. Kenyon

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Aleutian mink disease virus (ADV), propagated in normal mink kidney cell cultures, was resolved by centrifugation on CsCl density gradients into two components of densities 1.334 and 1.295 gm/cm3 which were, respectively, about 85 and 15% of the total virus yield. Electron microscopic examination revealed that the major component contained predominantly intact virions of 25 nm in diameter which resembled virus particles with icosahedral structure while the minor component contained mainly empty capsids. Both the empty capsids and intact virus particles absorbed to immunoabsorbents prepared with IgG from chronically infected mink. The buoyant density, size, and structure of purified ADV are in common with viruses belonging to the picornavirus group.

Original languageEnglish (US)
Pages (from-to)575-580
Number of pages6
JournalVirology
Volume64
Issue number2
DOIs
StatePublished - 1975
Externally publishedYes

Fingerprint

Aleutian Mink Disease Virus
Virion
Mink
Capsid
Viruses
Picornaviridae
Centrifugation
Cell Culture Techniques
Immunoglobulin G
Electrons
Kidney

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

Cite this

Characterization of aleutian mink disease virus. / Yoon, Ji Won; Dunker, A.; Kenyon, A. J.

In: Virology, Vol. 64, No. 2, 1975, p. 575-580.

Research output: Contribution to journalArticle

Yoon, Ji Won ; Dunker, A. ; Kenyon, A. J. / Characterization of aleutian mink disease virus. In: Virology. 1975 ; Vol. 64, No. 2. pp. 575-580.
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