Characterization of human hematopoietic stem cells.

J. E. Brandt, Edward Srour, K. van Besien, R. Hoffman

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

These data clearly indicate that suitable systems are presently available to isolate the human hematopoietic stem cell. The CFU-B1 and cells responsible for initiating long term hematopoiesis in vitro are likely identical since they share the same phenotype, CD34+DR-CD33-CD15-C71-. The suspension culture system as indicated above has several advantages over an adherent cell based long term marrow culture system. Use of this suspension culture system with 48 hourly feeding with recombinant cytokines will facilitate definition of the cytokine requirements for the human CFU-S.

Original languageEnglish
Pages (from-to)29-36
Number of pages8
JournalProgress in Clinical and Biological Research
Volume352
StatePublished - 1990

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Hematopoietic Stem Cells
Suspensions
Cytokines
Hematopoiesis
Bone Marrow
Phenotype
In Vitro Techniques

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Characterization of human hematopoietic stem cells. / Brandt, J. E.; Srour, Edward; van Besien, K.; Hoffman, R.

In: Progress in Clinical and Biological Research, Vol. 352, 1990, p. 29-36.

Research output: Contribution to journalArticle

Brandt, JE, Srour, E, van Besien, K & Hoffman, R 1990, 'Characterization of human hematopoietic stem cells.', Progress in Clinical and Biological Research, vol. 352, pp. 29-36.
Brandt, J. E. ; Srour, Edward ; van Besien, K. ; Hoffman, R. / Characterization of human hematopoietic stem cells. In: Progress in Clinical and Biological Research. 1990 ; Vol. 352. pp. 29-36.
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