Abstract
In a registry-based sample of 361 children with a brain tumor, those whose grandparents and great-grandparents had a history of any kind of tumor were younger at the time of presentation than were those who lacked this family history (p=0.1). In post hoc analyses, the age difference was most apparent among children with cerebral tumors, and when family history was limited to brain tumors and to great-grandparents. These findings are in keeping with the hypothesis that a familial tumor diathesis contributes to an early age at onset of a brain tumor in some children.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 75-79 |
| Number of pages | 5 |
| Journal | Cancer Causes and Control |
| Volume | 1 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jul 1990 |
| Externally published | Yes |
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Keywords
- Brain
- child
- neoplasms
- theoretical models
ASJC Scopus subject areas
- Oncology
- Epidemiology
- Cancer Research
Cite this
Childhood brain tumor : presentation at younger age is associated with a family tumor history. / Sussman, Andrew; Leviton, Alan; Allred, Elizabeth N.; Aschenbrener, Carol; Austin, Donald F.; Gilles, Floyd H.; Hedley-Whyte, E. Tessa; Kolonel, Laurence N.; Lyon, Joseph L.; Swanson, G. Marie; West, Dee.
In: Cancer Causes and Control, Vol. 1, No. 1, 07.1990, p. 75-79.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Childhood brain tumor
T2 - presentation at younger age is associated with a family tumor history
AU - Sussman, Andrew
AU - Leviton, Alan
AU - Allred, Elizabeth N.
AU - Aschenbrener, Carol
AU - Austin, Donald F.
AU - Gilles, Floyd H.
AU - Hedley-Whyte, E. Tessa
AU - Kolonel, Laurence N.
AU - Lyon, Joseph L.
AU - Swanson, G. Marie
AU - West, Dee
PY - 1990/7
Y1 - 1990/7
N2 - In a registry-based sample of 361 children with a brain tumor, those whose grandparents and great-grandparents had a history of any kind of tumor were younger at the time of presentation than were those who lacked this family history (p=0.1). In post hoc analyses, the age difference was most apparent among children with cerebral tumors, and when family history was limited to brain tumors and to great-grandparents. These findings are in keeping with the hypothesis that a familial tumor diathesis contributes to an early age at onset of a brain tumor in some children.
AB - In a registry-based sample of 361 children with a brain tumor, those whose grandparents and great-grandparents had a history of any kind of tumor were younger at the time of presentation than were those who lacked this family history (p=0.1). In post hoc analyses, the age difference was most apparent among children with cerebral tumors, and when family history was limited to brain tumors and to great-grandparents. These findings are in keeping with the hypothesis that a familial tumor diathesis contributes to an early age at onset of a brain tumor in some children.
KW - Brain
KW - child
KW - neoplasms
KW - theoretical models
UR - http://www.scopus.com/inward/record.url?scp=0025461860&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025461860&partnerID=8YFLogxK
U2 - 10.1007/BF00053186
DO - 10.1007/BF00053186
M3 - Article
C2 - 2102279
AN - SCOPUS:0025461860
VL - 1
SP - 75
EP - 79
JO - Cancer Causes and Control
JF - Cancer Causes and Control
SN - 0957-5243
IS - 1
ER -