Childhood brain tumor: presentation at younger age is associated with a family tumor history

Andrew Sussman; Alan Leviton; Elizabeth N. Allred; Carol Aschenbrener; Donald F. Austin; Floyd H. Gilles; E. Tessa Hedley-Whyte; Laurence N. Kolonel; Joseph L. Lyon; G. Marie Swanson; Dee West

doi:10.1007/BF00053186

Childhood brain tumor: presentation at younger age is associated with a family tumor history

Andrew Sussman, Alan Leviton, Elizabeth N. Allred, Carol Aschenbrener, Donald F. Austin, Floyd H. Gilles, E. Tessa Hedley-Whyte, Laurence N. Kolonel, Joseph L. Lyon, G. Marie Swanson, Dee West

Research output: Contribution to journal › Article

13 Scopus citations

Abstract

In a registry-based sample of 361 children with a brain tumor, those whose grandparents and great-grandparents had a history of any kind of tumor were younger at the time of presentation than were those who lacked this family history (p=0.1). In post hoc analyses, the age difference was most apparent among children with cerebral tumors, and when family history was limited to brain tumors and to great-grandparents. These findings are in keeping with the hypothesis that a familial tumor diathesis contributes to an early age at onset of a brain tumor in some children.

Original language	English (US)
Pages (from-to)	75-79
Number of pages	5
Journal	Cancer Causes and Control
Volume	1
Issue number	1
DOIs	https://doi.org/10.1007/BF00053186
State	Published - Jul 1 1990

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Keywords

Brain
child
neoplasms
theoretical models

ASJC Scopus subject areas

Oncology
Cancer Research

Cite this

Sussman, A., Leviton, A., Allred, E. N., Aschenbrener, C., Austin, D. F., Gilles, F. H., Hedley-Whyte, E. T., Kolonel, L. N., Lyon, J. L., Swanson, G. M., & West, D. (1990). Childhood brain tumor: presentation at younger age is associated with a family tumor history. Cancer Causes and Control, 1(1), 75-79. https://doi.org/10.1007/BF00053186

Childhood brain tumor : presentation at younger age is associated with a family tumor history. / Sussman, Andrew; Leviton, Alan; Allred, Elizabeth N.; Aschenbrener, Carol; Austin, Donald F.; Gilles, Floyd H.; Hedley-Whyte, E. Tessa; Kolonel, Laurence N.; Lyon, Joseph L.; Swanson, G. Marie; West, Dee.

In: Cancer Causes and Control, Vol. 1, No. 1, 01.07.1990, p. 75-79.

Research output: Contribution to journal › Article

Sussman, Andrew ; Leviton, Alan ; Allred, Elizabeth N. ; Aschenbrener, Carol ; Austin, Donald F. ; Gilles, Floyd H. ; Hedley-Whyte, E. Tessa ; Kolonel, Laurence N. ; Lyon, Joseph L. ; Swanson, G. Marie ; West, Dee. / Childhood brain tumor : presentation at younger age is associated with a family tumor history. In: Cancer Causes and Control. 1990 ; Vol. 1, No. 1. pp. 75-79.

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10.1007/BF00053186