Abstract
In a registry-based sample of 361 children with a brain tumor, those whose grandparents and great-grandparents had a history of any kind of tumor were younger at the time of presentation than were those who lacked this family history (p=0.1). In post hoc analyses, the age difference was most apparent among children with cerebral tumors, and when family history was limited to brain tumors and to great-grandparents. These findings are in keeping with the hypothesis that a familial tumor diathesis contributes to an early age at onset of a brain tumor in some children.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 75-79 |
| Number of pages | 5 |
| Journal | Cancer Causes and Control |
| Volume | 1 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jul 1 1990 |
Keywords
- Brain
- child
- neoplasms
- theoretical models
ASJC Scopus subject areas
- Oncology
- Cancer Research
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Sussman, A., Leviton, A., Allred, E. N., Aschenbrener, C., Austin, D. F., Gilles, F. H., Hedley-Whyte, E. T., Kolonel, L. N., Lyon, J. L., Swanson, G. M., & West, D. (1990). Childhood brain tumor: presentation at younger age is associated with a family tumor history. Cancer Causes and Control, 1(1), 75-79. https://doi.org/10.1007/BF00053186