Children with hepatitis C

Girish Subba Rao, Jean Molleston

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Hepatitis C affects thousands of children throughout the world. Most children acquire the virus through vertical transmission, although parenteral routes of acquisition are also common. Hepatitis C progresses slowly, with mild biopsy findings and no symptoms in most children and in many adults. However, significant liver inflammation and fibrosis can occur in childhood. Trials of antiviral therapy with interferon and ribavirin have shown these drugs to be effective in almost half of the children treated. Children tend to tolerate therapy well. Further research on the natural history and treatment of hepatitis C in children is needed because the infection can have serious long-term consequences, including end-stage liver disease and hepatocellular carcinoma.

Original languageEnglish
Pages (from-to)37-44
Number of pages8
JournalCurrent Gastroenterology Reports
Volume7
Issue number1
DOIs
StatePublished - 2005

Fingerprint

Hepatitis C
End Stage Liver Disease
Ribavirin
Natural History
Liver Cirrhosis
Interferons
Antiviral Agents
Hepatocellular Carcinoma
Therapeutics
Viruses
Inflammation
Biopsy
Infection
Research
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Gastroenterology
  • Medicine(all)

Cite this

Children with hepatitis C. / Rao, Girish Subba; Molleston, Jean.

In: Current Gastroenterology Reports, Vol. 7, No. 1, 2005, p. 37-44.

Research output: Contribution to journalArticle

Rao, Girish Subba ; Molleston, Jean. / Children with hepatitis C. In: Current Gastroenterology Reports. 2005 ; Vol. 7, No. 1. pp. 37-44.
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