Chlamydia trachomatis pneumonia induces in vivo production of interleukin- 1 and -6

D. M. Magee, J. G. Smith, C. A. Bleicker, C. J. Carter, Lynda Bonewald, J. Schachter, D. M. Williams

Research output: Contribution to journalComment/debate

34 Citations (Scopus)

Abstract

Cytokine induction during Chlamydia trachomatis pneumonia may alter the pathogenesis or course of disease. We examined interleukin-1 (IL-1) and IL-6 production by measuring mRNA and bioactivity in murine lungs. mRNA and bioactivity for IL-1α, IL-1β, and IL-6 increased after Chlamydia infection. These cytokines may be important in regulating host defenses against C. trachomatis.

Original languageEnglish (US)
Pages (from-to)1217-1220
Number of pages4
JournalInfection and Immunity
Volume60
Issue number3
StatePublished - 1992
Externally publishedYes

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Chlamydophila pneumoniae
Chlamydia trachomatis
Interleukin-1
Interleukin-6
Cytokines
Messenger RNA
Chlamydia Infections
Lung

ASJC Scopus subject areas

  • Immunology

Cite this

Magee, D. M., Smith, J. G., Bleicker, C. A., Carter, C. J., Bonewald, L., Schachter, J., & Williams, D. M. (1992). Chlamydia trachomatis pneumonia induces in vivo production of interleukin- 1 and -6. Infection and Immunity, 60(3), 1217-1220.

Chlamydia trachomatis pneumonia induces in vivo production of interleukin- 1 and -6. / Magee, D. M.; Smith, J. G.; Bleicker, C. A.; Carter, C. J.; Bonewald, Lynda; Schachter, J.; Williams, D. M.

In: Infection and Immunity, Vol. 60, No. 3, 1992, p. 1217-1220.

Research output: Contribution to journalComment/debate

Magee, DM, Smith, JG, Bleicker, CA, Carter, CJ, Bonewald, L, Schachter, J & Williams, DM 1992, 'Chlamydia trachomatis pneumonia induces in vivo production of interleukin- 1 and -6', Infection and Immunity, vol. 60, no. 3, pp. 1217-1220.
Magee DM, Smith JG, Bleicker CA, Carter CJ, Bonewald L, Schachter J et al. Chlamydia trachomatis pneumonia induces in vivo production of interleukin- 1 and -6. Infection and Immunity. 1992;60(3):1217-1220.
Magee, D. M. ; Smith, J. G. ; Bleicker, C. A. ; Carter, C. J. ; Bonewald, Lynda ; Schachter, J. ; Williams, D. M. / Chlamydia trachomatis pneumonia induces in vivo production of interleukin- 1 and -6. In: Infection and Immunity. 1992 ; Vol. 60, No. 3. pp. 1217-1220.
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