Choledochoceles: Are they choledochal cysts?

Kathryn M. Ziegler, Henry A. Pitt, Nicholas J. Zyromski, Aakash Chauhan, Stuart Sherman, Dana Moffatt, Glen A. Lehman, Keith D. Lillemoe, Frederick J. Rescorla, Karen W. West, Jay L. Grosfeld

Research output: Contribution to journalArticle

39 Scopus citations


Objective: The aim of this analysis was to report a multidisciplinary series comparing choledochoceles to Todani Types I, II, IV, and V choledochal cysts. Summary Background Data: Choledochoceles have been classified as Todani Type III choledochal cysts. However, most surgical series of choledochal cysts have reported few choledochoceles because they are managed primarily by endoscopists. Methods: Surgical, endoscopic, and radiologic records were reviewed at the Riley Children's Hospital and the Indiana University Hospitals to identify patients with choledochal cysts. Patient demographics, presenting symptoms, radiologic studies, associated abnormalities, surgical and endoscopic procedures as well as outcomes were reviewed. Results: A total of 146 patients with "choledochal cysts" including 45 children (31%) and 28 with choledochoceles (18%) were identified, which represents the largest Western series. Patients with choledochoceles were older (50.7 vs. 29.0 years, P < 0.05) and more likely to be male (43% vs. 19%, P < 0.05), to present with pancreatitis (48% vs. 24%, P < 0.05) rather than jaundice (11% vs. 30%, P < 0.05) or cholangitis (0% vs. 21%, P < 0.05), to have pancreas divisum (38% vs. 10%, P < 0.01), and to be managed with endoscopic therapy (79% vs. 17%, P < 0.01). Two patients with choledochoceles (7%) had pancreatic neoplasms. Conclusions: Patients with choledochoceles differ from patients with choledochal cysts with respect to age, gender, presentation, pancreatic ductal anatomy, and their management. The association between choledochoceles and pancreas divisum is a new observation. Therefore, we conclude that classifications of choledochal cysts should not include choledochoceles.

Original languageEnglish (US)
Pages (from-to)683-689
Number of pages7
JournalAnnals of surgery
Issue number4
StatePublished - Oct 1 2010

ASJC Scopus subject areas

  • Surgery

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    Ziegler, K. M., Pitt, H. A., Zyromski, N. J., Chauhan, A., Sherman, S., Moffatt, D., Lehman, G. A., Lillemoe, K. D., Rescorla, F. J., West, K. W., & Grosfeld, J. L. (2010). Choledochoceles: Are they choledochal cysts? Annals of surgery, 252(4), 683-689.