A 69-year-old woman underwent a hysterectomy and bilateral salpingo-oophorectomy for a 20-cm right ovarian tumor. Multiple peritoneal and lymph node biopsy specimens were obtained to determine the clinical stage. Despite the surgeon's concern of malignancy, pathologic examination demonstrated a benign mucinous cystadenoma. Periaortic and external iliac lymph nodes showed an unusual granulomatous reaction, with multinucleated giant cells surrounding cholesterol-like clefts. Analysis of cyst fluid from the ovarian tumor revealed high concentrations of protein and lipid; the lipid component was predominantly free cholesterol (0.61 μmole/mL) and phospholipid (0.225 μmole/mL). We speculate that fluid from the ovarian neoplasm drained into regional lymph nodes, causing this unusual granulomatous response.
|Original language||English (US)|
|Number of pages||3|
|Journal||Archives of Pathology and Laboratory Medicine|
|State||Published - Dec 1 1985|
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Medical Laboratory Technology