Chromosome localization of the human renin gene (REN) by in situ hybridization

J. R. McGill, John Chirgwin, C. M. Moore, J. L. McCombs

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Previous studies by Southern blot analysis of human x mouse somatic cell hybrids localized the renin gene to region p21→qter of human chromosome 1. Using a DNA insert encoding exons 2-5, the renin gene was mapped to human chromosome bands 1q25→q32 by in situ hybridization. The sublocalization of the renin gene will facilitate subsequent detailed linkage analysis of human chromosome 1.

Original languageEnglish (US)
Pages (from-to)55-57
Number of pages3
JournalCytogenetics and Cell Genetics
Volume45
Issue number1
StatePublished - 1987
Externally publishedYes

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Human Chromosomes
Renin
In Situ Hybridization
Chromosomes, Human, Pair 1
Genes
Hybrid Cells
Southern Blotting
Exons
DNA

ASJC Scopus subject areas

  • Cell Biology
  • Genetics

Cite this

Chromosome localization of the human renin gene (REN) by in situ hybridization. / McGill, J. R.; Chirgwin, John; Moore, C. M.; McCombs, J. L.

In: Cytogenetics and Cell Genetics, Vol. 45, No. 1, 1987, p. 55-57.

Research output: Contribution to journalArticle

McGill, J. R. ; Chirgwin, John ; Moore, C. M. ; McCombs, J. L. / Chromosome localization of the human renin gene (REN) by in situ hybridization. In: Cytogenetics and Cell Genetics. 1987 ; Vol. 45, No. 1. pp. 55-57.
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