Chronic fatigue syndrome: Is it real?

Research output: Contribution to journalReview article

9 Scopus citations


Epstein-Barr virus is no longer considered an important cause of chronic fatigue syndrome. Instead, the disease is probably related to an underlying psychiatric disorder, subtle immunologic dysfunction, or an interaction between these two factors. A carefully taken history, physical examination, and simple laboratory testing are usually sufficient to establish the diagnosis. Therapy with antidepressants or nonsteroidal antiinflammatory drugs may be effective in selected patients. Thorough follow-up conducted with empathy and optimism is important in all cases.

Original languageEnglish (US)
Pages (from-to)44-46+49
JournalPostgraduate Medicine
Issue number2
StatePublished - Jan 1 1991
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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