Circulating and tissue resident endothelial progenitor cells.

Research output: Contribution to journalArticle

112 Citations (Scopus)

Abstract

Progenitor cells for the endothelial lineage have been widely investigated for more than a decade, but continue to be controversial since no unique identifying marker has yet been identified. This review will begin with a discussion of the basic tenets originally proposed for proof that a cell displays properties of an endothelial progenitor cell. We then provide an overview of the methods for putative endothelial progenitor cell derivation, expansion, and enumeration. This discussion includes consideration of cells that are present in the circulation as well as cells resident in the vascular endothelial intima. Finally, we provide some suggested changes in nomenclature that would greatly clarify and demystify the cellular elements involved in vascular repair.

Original languageEnglish
Pages (from-to)10-16
Number of pages7
JournalJournal of Cellular Physiology
Volume229
Issue number1
StatePublished - Jan 2014

Fingerprint

Endothelial cells
Tissue
Terminology
Tunica Intima
Repair
Cell Lineage
Blood Vessels
Stem Cells
Endothelial Progenitor Cells

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Cell Biology
  • Physiology
  • Medicine(all)

Cite this

Circulating and tissue resident endothelial progenitor cells. / Basile, David; Yoder, Mervin.

In: Journal of Cellular Physiology, Vol. 229, No. 1, 01.2014, p. 10-16.

Research output: Contribution to journalArticle

@article{df932a6ff8a748ada95cc65d92765426,
title = "Circulating and tissue resident endothelial progenitor cells.",
abstract = "Progenitor cells for the endothelial lineage have been widely investigated for more than a decade, but continue to be controversial since no unique identifying marker has yet been identified. This review will begin with a discussion of the basic tenets originally proposed for proof that a cell displays properties of an endothelial progenitor cell. We then provide an overview of the methods for putative endothelial progenitor cell derivation, expansion, and enumeration. This discussion includes consideration of cells that are present in the circulation as well as cells resident in the vascular endothelial intima. Finally, we provide some suggested changes in nomenclature that would greatly clarify and demystify the cellular elements involved in vascular repair.",
author = "David Basile and Mervin Yoder",
year = "2014",
month = "1",
language = "English",
volume = "229",
pages = "10--16",
journal = "Journal of Cellular Physiology",
issn = "0021-9541",
publisher = "Wiley-Liss Inc.",
number = "1",

}

TY - JOUR

T1 - Circulating and tissue resident endothelial progenitor cells.

AU - Basile, David

AU - Yoder, Mervin

PY - 2014/1

Y1 - 2014/1

N2 - Progenitor cells for the endothelial lineage have been widely investigated for more than a decade, but continue to be controversial since no unique identifying marker has yet been identified. This review will begin with a discussion of the basic tenets originally proposed for proof that a cell displays properties of an endothelial progenitor cell. We then provide an overview of the methods for putative endothelial progenitor cell derivation, expansion, and enumeration. This discussion includes consideration of cells that are present in the circulation as well as cells resident in the vascular endothelial intima. Finally, we provide some suggested changes in nomenclature that would greatly clarify and demystify the cellular elements involved in vascular repair.

AB - Progenitor cells for the endothelial lineage have been widely investigated for more than a decade, but continue to be controversial since no unique identifying marker has yet been identified. This review will begin with a discussion of the basic tenets originally proposed for proof that a cell displays properties of an endothelial progenitor cell. We then provide an overview of the methods for putative endothelial progenitor cell derivation, expansion, and enumeration. This discussion includes consideration of cells that are present in the circulation as well as cells resident in the vascular endothelial intima. Finally, we provide some suggested changes in nomenclature that would greatly clarify and demystify the cellular elements involved in vascular repair.

UR - http://www.scopus.com/inward/record.url?scp=84887521005&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84887521005&partnerID=8YFLogxK

M3 - Article

C2 - 23794280

AN - SCOPUS:84887521005

VL - 229

SP - 10

EP - 16

JO - Journal of Cellular Physiology

JF - Journal of Cellular Physiology

SN - 0021-9541

IS - 1

ER -