cis-Platinum in advanced gynecologic malignancy

Frederick Stehman, Samuel C. Ballon, Leo D. Lagasse, Terry P. Chamorro, Robert C. Donaldson, James A. Roberts, Larry C. Ford

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Eighteen patients with advanced gynecologic malignancies received cis-diamminedichloroplatinum (NSC 119875), an inorganic heavy metal compound with antineoplastic properties. Twelve patients had carcinoma of the ovary resistant to other chemotherapeutic agents. Three patients had previously irradiated carcinoma of the cervix; two, disseminated pelvic sarcoma; and one, metastatic carcinoma of the vulva. Objective responses were achieved in four patients (25%) with carcinoma of the ovary. Three patients with other tumors also responded. Mild to severe myelosuppression, nephrotoxicity, and ototoxicity occurred.

Original languageEnglish (US)
Pages (from-to)349-360
Number of pages12
JournalGynecologic Oncology
Volume7
Issue number3
DOIs
StatePublished - 1979
Externally publishedYes

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Cisplatin
Carcinoma
Neoplasms
Ovary
Vulva
Heavy Metals
Cervix Uteri
Sarcoma
Antineoplastic Agents

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Oncology

Cite this

Stehman, F., Ballon, S. C., Lagasse, L. D., Chamorro, T. P., Donaldson, R. C., Roberts, J. A., & Ford, L. C. (1979). cis-Platinum in advanced gynecologic malignancy. Gynecologic Oncology, 7(3), 349-360. https://doi.org/10.1016/0090-8258(79)90113-6

cis-Platinum in advanced gynecologic malignancy. / Stehman, Frederick; Ballon, Samuel C.; Lagasse, Leo D.; Chamorro, Terry P.; Donaldson, Robert C.; Roberts, James A.; Ford, Larry C.

In: Gynecologic Oncology, Vol. 7, No. 3, 1979, p. 349-360.

Research output: Contribution to journalArticle

Stehman, F, Ballon, SC, Lagasse, LD, Chamorro, TP, Donaldson, RC, Roberts, JA & Ford, LC 1979, 'cis-Platinum in advanced gynecologic malignancy', Gynecologic Oncology, vol. 7, no. 3, pp. 349-360. https://doi.org/10.1016/0090-8258(79)90113-6
Stehman F, Ballon SC, Lagasse LD, Chamorro TP, Donaldson RC, Roberts JA et al. cis-Platinum in advanced gynecologic malignancy. Gynecologic Oncology. 1979;7(3):349-360. https://doi.org/10.1016/0090-8258(79)90113-6
Stehman, Frederick ; Ballon, Samuel C. ; Lagasse, Leo D. ; Chamorro, Terry P. ; Donaldson, Robert C. ; Roberts, James A. ; Ford, Larry C. / cis-Platinum in advanced gynecologic malignancy. In: Gynecologic Oncology. 1979 ; Vol. 7, No. 3. pp. 349-360.
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