Abstract
The morphological features and immunohistochemical findings of two cases of clear cell renal cell carcinoma with extensive hemangioblastoma-like features are described. To the best of our knowledge, this is the first description of such a pattern, the differential diagnosis being with renal hemangioblastoma, a rare tumor that could be considered a diffuse hemangioblastoma-like change in a clear cell renal cell tumor. Even though the clinical significance and therapeutic implications are not yet known, the hemangioblastoma-like pattern could have favorable prognostic significance based on the fact that the renal hemangioblastomas described so far have benign behavior.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 806-810 |
| Number of pages | 5 |
| Journal | European Urology |
| Volume | 66 |
| Issue number | 5 |
| DOIs | |
| State | Published - Nov 1 2014 |
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Keywords
- Clear cell renal cell carcinoma
- Hemangioblastoma
- Hemangioblastoma-like ccRCC
- PAX8
ASJC Scopus subject areas
- Urology
- Medicine(all)
Cite this
Clear cell renal cell carcinoma (ccRCC) with hemangioblastoma-like features : A previously unreported pattern of ccRCC with possible clinical significance. / Montironi, Rodolfo; Lopez-Beltran, Antonio; Cheng, Liang; Galosi, Andrea B.; Montorsi, Francesco; Scarpelli, Marina.
In: European Urology, Vol. 66, No. 5, 01.11.2014, p. 806-810.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Clear cell renal cell carcinoma (ccRCC) with hemangioblastoma-like features
T2 - A previously unreported pattern of ccRCC with possible clinical significance
AU - Montironi, Rodolfo
AU - Lopez-Beltran, Antonio
AU - Cheng, Liang
AU - Galosi, Andrea B.
AU - Montorsi, Francesco
AU - Scarpelli, Marina
PY - 2014/11/1
Y1 - 2014/11/1
N2 - The morphological features and immunohistochemical findings of two cases of clear cell renal cell carcinoma with extensive hemangioblastoma-like features are described. To the best of our knowledge, this is the first description of such a pattern, the differential diagnosis being with renal hemangioblastoma, a rare tumor that could be considered a diffuse hemangioblastoma-like change in a clear cell renal cell tumor. Even though the clinical significance and therapeutic implications are not yet known, the hemangioblastoma-like pattern could have favorable prognostic significance based on the fact that the renal hemangioblastomas described so far have benign behavior.
AB - The morphological features and immunohistochemical findings of two cases of clear cell renal cell carcinoma with extensive hemangioblastoma-like features are described. To the best of our knowledge, this is the first description of such a pattern, the differential diagnosis being with renal hemangioblastoma, a rare tumor that could be considered a diffuse hemangioblastoma-like change in a clear cell renal cell tumor. Even though the clinical significance and therapeutic implications are not yet known, the hemangioblastoma-like pattern could have favorable prognostic significance based on the fact that the renal hemangioblastomas described so far have benign behavior.
KW - Clear cell renal cell carcinoma
KW - Hemangioblastoma
KW - Hemangioblastoma-like ccRCC
KW - PAX8
UR - http://www.scopus.com/inward/record.url?scp=84907586179&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84907586179&partnerID=8YFLogxK
U2 - 10.1016/j.eururo.2014.04.022
DO - 10.1016/j.eururo.2014.04.022
M3 - Article
C2 - 24821578
AN - SCOPUS:84907586179
VL - 66
SP - 806
EP - 810
JO - European Urology
JF - European Urology
SN - 0302-2838
IS - 5
ER -