Clear cell renal cell carcinoma (ccRCC) with hemangioblastoma-like features: A previously unreported pattern of ccRCC with possible clinical significance

Rodolfo Montironi, Antonio Lopez-Beltran, Liang Cheng, Andrea B. Galosi, Francesco Montorsi, Marina Scarpelli

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

The morphological features and immunohistochemical findings of two cases of clear cell renal cell carcinoma with extensive hemangioblastoma-like features are described. To the best of our knowledge, this is the first description of such a pattern, the differential diagnosis being with renal hemangioblastoma, a rare tumor that could be considered a diffuse hemangioblastoma-like change in a clear cell renal cell tumor. Even though the clinical significance and therapeutic implications are not yet known, the hemangioblastoma-like pattern could have favorable prognostic significance based on the fact that the renal hemangioblastomas described so far have benign behavior.

Original languageEnglish (US)
Pages (from-to)806-810
Number of pages5
JournalEuropean urology
Volume66
Issue number5
DOIs
StatePublished - Nov 1 2014

Keywords

  • Clear cell renal cell carcinoma
  • Hemangioblastoma
  • Hemangioblastoma-like ccRCC
  • PAX8

ASJC Scopus subject areas

  • Urology

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