Clinical and educational impact of pharmacogenomics testing: A case series from the INGENIOUS trial

Rebecca C. Pierson, Brandon T. Gufford, Zeruesenay Desta, Michael T. Eadon

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Pharmacogenomic testing has become increasingly widespread. However, there remains a need to bridge the gap between test results and providers lacking the expertise required to interpret these results. The Indiana Genomics Implementation trial is underway at our institution to examine total healthcare cost and patient outcomes after genotyping in a safety-net healthcare system. As part of the study, trial investigators and clinical pharmacology fellows interpret genotype results, review patient histories and medication lists and evaluate potential drug-drug interactions. We present a case series of patients in whom pharmacogenomic consultations aided providers in appropriately applying pharmacogenomic results within the clinical context. Formal consultations not only provide valuable patient care information but educational opportunities for the fellows to cement pharmacogenomic concepts.

Original languageEnglish (US)
Pages (from-to)835-841
Number of pages7
JournalPharmacogenomics
Volume18
Issue number9
DOIs
StatePublished - Jun 2017

Keywords

  • clinical
  • education
  • genetic testing
  • pharmacogenetics
  • pharmacology
  • precision medicine

ASJC Scopus subject areas

  • Molecular Medicine
  • Genetics
  • Pharmacology

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