Presentación clínica y patológica de un paciente portador de síndrome de alport

Translated title of the contribution: Clinical and pathological presentation of an alport syndrome carrier patient

L. López, Robert Bacallao, L. González, Y. Chávez, M. Matos, F. Reinol, M. Benchimol

Research output: Contribution to journalArticle

Abstract

Renal histopathological findings and prognosis of chronic kidney disease of an Alport syndrome carrier patient is shown. Alport syndrome is an inherited disorder caused by progressive alterations of collagen synthesis and affects kidney function, hearing and vision. Case: Young man, caucasian, history of hypertension for three years, hospitalized for a hypertensive emergency, also referred foamy urine and edema, suspected glomerulopathy. Laboratory analysis revealed proteinuria of 8.7 g/day, glomerular hematuria and elevated serum creatinine. Renal biopsy was obtained and special techniques, immunofluorescence and ultrastructural studies were performed. A patient with an Alport syndrome with a pattern of focal segmental glomerulosclerosis is presented. The presence of this disease in other family members was found. The histological study allowed us to determined the unfavorable prognosis of chronic kidney disease in this patient.

Original languageSpanish
Pages (from-to)132-139
Number of pages8
JournalActa Microscopica
Volume21
Issue number3
StatePublished - 2012
Externally publishedYes

Fingerprint

Hereditary Nephritis
kidney diseases
prognosis
Chronic Renal Insufficiency
Kidney
hematuria
creatinine
hypertension
Focal Segmental Glomerulosclerosis
edema
urine
Biopsy
emergencies
Audition
kidneys
Hematuria
collagens
hearing
Proteinuria
Collagen

Keywords

  • Alport syndrome
  • Focal and segmental glomerulosclerosis
  • Hereditary nephropathy

ASJC Scopus subject areas

  • Instrumentation
  • Materials Science(all)
  • Microbiology (medical)

Cite this

López, L., Bacallao, R., González, L., Chávez, Y., Matos, M., Reinol, F., & Benchimol, M. (2012). Presentación clínica y patológica de un paciente portador de síndrome de alport. Acta Microscopica, 21(3), 132-139.

Presentación clínica y patológica de un paciente portador de síndrome de alport. / López, L.; Bacallao, Robert; González, L.; Chávez, Y.; Matos, M.; Reinol, F.; Benchimol, M.

In: Acta Microscopica, Vol. 21, No. 3, 2012, p. 132-139.

Research output: Contribution to journalArticle

López, L, Bacallao, R, González, L, Chávez, Y, Matos, M, Reinol, F & Benchimol, M 2012, 'Presentación clínica y patológica de un paciente portador de síndrome de alport', Acta Microscopica, vol. 21, no. 3, pp. 132-139.
López L, Bacallao R, González L, Chávez Y, Matos M, Reinol F et al. Presentación clínica y patológica de un paciente portador de síndrome de alport. Acta Microscopica. 2012;21(3):132-139.
López, L. ; Bacallao, Robert ; González, L. ; Chávez, Y. ; Matos, M. ; Reinol, F. ; Benchimol, M. / Presentación clínica y patológica de un paciente portador de síndrome de alport. In: Acta Microscopica. 2012 ; Vol. 21, No. 3. pp. 132-139.
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