Clinical and Research Considerations for Patients With Hypertensive Acute Heart Failure: A Consensus Statement from the Society of Academic Emergency Medicine and the Heart Failure Society of America Acute Heart Failure Working Group

Sean P. Collins, Phillip D. Levy, Jennifer L. Martindale, Mark E. Dunlap, Alan B. Storrow, Peter Pang, Nancy M. Albert, G. Michael Felker, Gregory J. Fermann, Gregg C. Fonarow, Michael M. Givertz, Judd E. Hollander, David J. Lanfear, Daniel J. Lenihan, Jo Ann M Lindenfeld, W. Frank Peacock, Douglas B. Sawyer, John R. Teerlink, Javed Butler

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Management approaches for patients in the emergency department (ED) who present with acute heart failure (AHF) have largely focused on intravenous diuretics. Yet, the primary pathophysiologic derangement underlying AHF in many patients is not solely volume overload. Patients with hypertensive AHF (H-AHF) represent a clinical phenotype with distinct pathophysiologic mechanisms that result in elevated ventricular filling pressures. To optimize treatment response and minimize adverse events in this subgroup, we propose that clinical management be tailored to a conceptual model of disease based on these mechanisms. This consensus statement reviews the relevant pathophysiology, clinical characteristics, approach to therapy, and considerations for clinical trials in ED patients with H-AHF.

Original languageEnglish (US)
JournalJournal of Cardiac Failure
DOIs
StateAccepted/In press - Oct 12 2015

Fingerprint

Emergency Medicine
Heart Failure
Research
Hospital Emergency Service
Ventricular Pressure
Diuretics
Clinical Trials
Phenotype
Therapeutics

Keywords

  • Emergency
  • Heart failure
  • Hypertension

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Clinical and Research Considerations for Patients With Hypertensive Acute Heart Failure : A Consensus Statement from the Society of Academic Emergency Medicine and the Heart Failure Society of America Acute Heart Failure Working Group. / Collins, Sean P.; Levy, Phillip D.; Martindale, Jennifer L.; Dunlap, Mark E.; Storrow, Alan B.; Pang, Peter; Albert, Nancy M.; Felker, G. Michael; Fermann, Gregory J.; Fonarow, Gregg C.; Givertz, Michael M.; Hollander, Judd E.; Lanfear, David J.; Lenihan, Daniel J.; Lindenfeld, Jo Ann M; Peacock, W. Frank; Sawyer, Douglas B.; Teerlink, John R.; Butler, Javed.

In: Journal of Cardiac Failure, 12.10.2015.

Research output: Contribution to journalArticle

Collins, SP, Levy, PD, Martindale, JL, Dunlap, ME, Storrow, AB, Pang, P, Albert, NM, Felker, GM, Fermann, GJ, Fonarow, GC, Givertz, MM, Hollander, JE, Lanfear, DJ, Lenihan, DJ, Lindenfeld, JAM, Peacock, WF, Sawyer, DB, Teerlink, JR & Butler, J 2015, 'Clinical and Research Considerations for Patients With Hypertensive Acute Heart Failure: A Consensus Statement from the Society of Academic Emergency Medicine and the Heart Failure Society of America Acute Heart Failure Working Group', Journal of Cardiac Failure. https://doi.org/10.1016/j.cardfail.2016.04.015
Collins, Sean P. ; Levy, Phillip D. ; Martindale, Jennifer L. ; Dunlap, Mark E. ; Storrow, Alan B. ; Pang, Peter ; Albert, Nancy M. ; Felker, G. Michael ; Fermann, Gregory J. ; Fonarow, Gregg C. ; Givertz, Michael M. ; Hollander, Judd E. ; Lanfear, David J. ; Lenihan, Daniel J. ; Lindenfeld, Jo Ann M ; Peacock, W. Frank ; Sawyer, Douglas B. ; Teerlink, John R. ; Butler, Javed. / Clinical and Research Considerations for Patients With Hypertensive Acute Heart Failure : A Consensus Statement from the Society of Academic Emergency Medicine and the Heart Failure Society of America Acute Heart Failure Working Group. In: Journal of Cardiac Failure. 2015.
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