Clinical and Research Considerations for Patients With Hypertensive Acute Heart Failure: A Consensus Statement from the Society for Academic Emergency Medicine and the Heart Failure Society of America Acute Heart Failure Working Group

Sean P. Collins, Phillip D. Levy, Jennifer L. Martindale, Mark E. Dunlap, Alan B. Storrow, Peter S. Pang, Nancy M. Albert, G. Michael Felker, Gregory J. Fermann, Gregg C. Fonarow, Michael M. Givertz, Judd E. Hollander, David E. Lanfear, Daniel J. Lenihan, Jo Ann M. Lindenfeld, W. Frank Peacock, Douglas B. Sawyer, John R. Teerlink, Javed Butler

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Management approaches for patients in the emergency department (ED) who present with acute heart failure (AHF) have largely focused on intravenous diuretics. Yet, the primary pathophysiologic derangement underlying AHF in many patients is not solely volume overload. Patients with hypertensive AHF (H-AHF) represent a clinical phenotype with distinct pathophysiologic mechanisms that result in elevated ventricular filling pressures. To optimize treatment response and minimize adverse events in this subgroup, we propose that clinical management be tailored to a conceptual model of disease that is based on these mechanisms. This consensus statement reviews the relevant pathophysiology, clinical characteristics, approach to therapy, and considerations for clinical trials in ED patients with H-AHF.

Original languageEnglish (US)
Pages (from-to)922-931
Number of pages10
JournalAcademic Emergency Medicine
Volume23
Issue number8
DOIs
StatePublished - Aug 1 2016

ASJC Scopus subject areas

  • Emergency Medicine

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    Collins, S. P., Levy, P. D., Martindale, J. L., Dunlap, M. E., Storrow, A. B., Pang, P. S., Albert, N. M., Felker, G. M., Fermann, G. J., Fonarow, G. C., Givertz, M. M., Hollander, J. E., Lanfear, D. E., Lenihan, D. J., Lindenfeld, J. A. M., Peacock, W. F., Sawyer, D. B., Teerlink, J. R., & Butler, J. (2016). Clinical and Research Considerations for Patients With Hypertensive Acute Heart Failure: A Consensus Statement from the Society for Academic Emergency Medicine and the Heart Failure Society of America Acute Heart Failure Working Group. Academic Emergency Medicine, 23(8), 922-931. https://doi.org/10.1111/acem.13025