Clinical correlates of cigarette smoking and nicotine dependence in alcohol-dependent men and women

Jean Bernard Daeppen, Tom L. Smith, George P. Danko, Lauren Gordon, Nancy A. Landi, John Nurnberger, Kathleen K. Bucholz, Eric Raimo, Marc A. Schuckit, T. K. Li, P. M. Conneally, Howard Edenberg, R. Crowe, S. Kuperman, F. Bloom, V. Hesselbrock, H. Begleiter, B. Porjesz, T. Reich, C. R. Cloninger & 1 others J. Rice

Research output: Contribution to journalArticle

108 Citations (Scopus)

Abstract

This paper examines the clinical characteristics associated with tobacco use and nicotine dependence in a large sample of alcohol-dependent subjects. The goal was to determine if the characteristics of the alcohol use history were associated with the smoking status, even after controlling for additional characteristics, such as the antisocial personality disorder, other drug dependence and gender. As part of the Collaborative Study on the Genetics of Alcoholism, a semi-structured interview, including a detailed history of alcohol and tobacco use, was administered to 1005 alcohol-dependent men and women, made up of 658 (65.5%) current smokers, 167 (16.6%) former smokers, and 180 (17.9%) non-smokers. Among former smokers, 50.3%, and among current smokers, 72.8% had ever been nicotine-dependent (DSM-III-R). Current smokers and nicotine-dependent subjects had a greater severity of alcohol dependence, even as evaluated through logistic regression analyses in which gender and associated diagnoses were considered. The data also enabled us to study the relationships among depression, nicotine dependence, and alcohol dependence, with most of the correlation occurring for substance-induced, not independent, mood disorders.

Original languageEnglish (US)
Pages (from-to)171-175
Number of pages5
JournalAlcohol and Alcoholism
Volume35
Issue number2
StatePublished - 2000
Externally publishedYes

Fingerprint

Tobacco Use Disorder
Nicotine
Tobacco Products
Smoking
Alcohols
Alcoholism
Tobacco Use
Tobacco
Antisocial Personality Disorder
Mood Disorders
Diagnostic and Statistical Manual of Mental Disorders
Substance-Related Disorders
Logistic Models
History
Regression Analysis
Interviews
Depression
Logistics
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Toxicology

Cite this

Daeppen, J. B., Smith, T. L., Danko, G. P., Gordon, L., Landi, N. A., Nurnberger, J., ... Rice, J. (2000). Clinical correlates of cigarette smoking and nicotine dependence in alcohol-dependent men and women. Alcohol and Alcoholism, 35(2), 171-175.

Clinical correlates of cigarette smoking and nicotine dependence in alcohol-dependent men and women. / Daeppen, Jean Bernard; Smith, Tom L.; Danko, George P.; Gordon, Lauren; Landi, Nancy A.; Nurnberger, John; Bucholz, Kathleen K.; Raimo, Eric; Schuckit, Marc A.; Li, T. K.; Conneally, P. M.; Edenberg, Howard; Crowe, R.; Kuperman, S.; Bloom, F.; Hesselbrock, V.; Begleiter, H.; Porjesz, B.; Reich, T.; Cloninger, C. R.; Rice, J.

In: Alcohol and Alcoholism, Vol. 35, No. 2, 2000, p. 171-175.

Research output: Contribution to journalArticle

Daeppen, JB, Smith, TL, Danko, GP, Gordon, L, Landi, NA, Nurnberger, J, Bucholz, KK, Raimo, E, Schuckit, MA, Li, TK, Conneally, PM, Edenberg, H, Crowe, R, Kuperman, S, Bloom, F, Hesselbrock, V, Begleiter, H, Porjesz, B, Reich, T, Cloninger, CR & Rice, J 2000, 'Clinical correlates of cigarette smoking and nicotine dependence in alcohol-dependent men and women', Alcohol and Alcoholism, vol. 35, no. 2, pp. 171-175.
Daeppen, Jean Bernard ; Smith, Tom L. ; Danko, George P. ; Gordon, Lauren ; Landi, Nancy A. ; Nurnberger, John ; Bucholz, Kathleen K. ; Raimo, Eric ; Schuckit, Marc A. ; Li, T. K. ; Conneally, P. M. ; Edenberg, Howard ; Crowe, R. ; Kuperman, S. ; Bloom, F. ; Hesselbrock, V. ; Begleiter, H. ; Porjesz, B. ; Reich, T. ; Cloninger, C. R. ; Rice, J. / Clinical correlates of cigarette smoking and nicotine dependence in alcohol-dependent men and women. In: Alcohol and Alcoholism. 2000 ; Vol. 35, No. 2. pp. 171-175.
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