Clinical experience with histidine-tryptophan-ketoglutarate solution in abdominal organ preservation

A review of recent literature

Jonathan A. Fridell, Richard Mangus, A. J. Tector

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Histidine-tryptophan-ketoglutarate (HTK) solution was introduced by Bretschneider as a cardioplegia solution in the early 1980s and has subsequently been applied to organ preservation for transplantation in Europe during the 1980s and in North America during the last six yr. With the increasing use of HTK for primary preservation, it is important that the transplant community be aware of the properties of this solution and the advantages and disadvantages of its use. Even if a center uses an alternative preservation solution, it is likely that import offers will be made for allografts that have been preserved in HTK. In this review article, recent literature describing the clinical use of HTK in abdominal transplantation will be summarized with references to earlier reports when indicated.

Original languageEnglish
Pages (from-to)305-312
Number of pages8
JournalClinical Transplantation
Volume23
Issue number3
DOIs
StatePublished - 2009

Fingerprint

Organ Preservation
Histidine
Tryptophan
Induced Heart Arrest
Organ Transplantation
North America
Allografts
Transplantation
Transplants
Bretschneider cardioplegic solution

Keywords

  • Histidine-tryptophan-ketoglutarate
  • Intestinal transplantation
  • Kidney transplantation
  • Liver transplantation
  • Pancreas transplantation
  • Preservation solutions

ASJC Scopus subject areas

  • Transplantation

Cite this

Clinical experience with histidine-tryptophan-ketoglutarate solution in abdominal organ preservation : A review of recent literature. / Fridell, Jonathan A.; Mangus, Richard; Tector, A. J.

In: Clinical Transplantation, Vol. 23, No. 3, 2009, p. 305-312.

Research output: Contribution to journalArticle

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