Clinical experience with histidine-tryptophan-ketoglutarate solution in abdominal organ preservation: A review of recent literature

Jonathan A. Fridell, Richard S. Mangus, A. J. Tector

Research output: Contribution to journalReview article

22 Scopus citations

Abstract

Histidine-tryptophan-ketoglutarate (HTK) solution was introduced by Bretschneider as a cardioplegia solution in the early 1980s and has subsequently been applied to organ preservation for transplantation in Europe during the 1980s and in North America during the last six yr. With the increasing use of HTK for primary preservation, it is important that the transplant community be aware of the properties of this solution and the advantages and disadvantages of its use. Even if a center uses an alternative preservation solution, it is likely that import offers will be made for allografts that have been preserved in HTK. In this review article, recent literature describing the clinical use of HTK in abdominal transplantation will be summarized with references to earlier reports when indicated.

Original languageEnglish (US)
Pages (from-to)305-312
Number of pages8
JournalClinical Transplantation
Volume23
Issue number3
DOIs
StatePublished - Jun 16 2009

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Keywords

  • Histidine-tryptophan-ketoglutarate
  • Intestinal transplantation
  • Kidney transplantation
  • Liver transplantation
  • Pancreas transplantation
  • Preservation solutions

ASJC Scopus subject areas

  • Transplantation

Cite this

Clinical experience with histidine-tryptophan-ketoglutarate solution in abdominal organ preservation : A review of recent literature. / Fridell, Jonathan A.; Mangus, Richard S.; Tector, A. J.

In: Clinical Transplantation, Vol. 23, No. 3, 16.06.2009, p. 305-312.

Research output: Contribution to journalReview article