Clinical outcomes and indicators of normalization of left ventricular dimensions after Ross procedure in children

John W. Brown, Mark Ruzmetov, Palaniswamy Vijay, Randall G. Bills, Mark W. Turrentine

Research output: Contribution to journalArticle

28 Scopus citations


Between 1993 and 2000, 50 patients (age range, 1 month to 18 years) who had left ventricular outflow tract (LVOT) disease and had undergone a Ross procedure were assessed using echocardiography. Aortic annulus size, valvular gradient, valve insufficiency, LV dimensions at end-systole and end-diastole, LV interventricular septal and posterior wall thickness, and LV mass index (LVMI) were measured. There was 1 early and 2 late deaths, and 5 reoperations. Aortic annulus size increased and degree of aortic insufficiency (AI) decreased, as did LV internal dimensions and LVMI. Peak pressure gradients declined from 73 ± 18 mm Hg to 7 ± 7 mm Hg, and LVMI regressed (167 ± 6 g/m2 v 108 ± 6 g/m2, P < .001) after 3 years. The degree of AI ranged from none to mild, and no patient has LVOT stenosis. Regression of LV dilatation and hypertrophy, good autograft valve function and durability, and a high survival rate suggest that the Ross procedure is preferred for most children who require aortic valve replacement.

Original languageEnglish (US)
Pages (from-to)28-34
Number of pages7
JournalSeminars in Thoracic and Cardiovascular Surgery
Issue number4 SUPPL. 1
StatePublished - Dec 1 2001



  • Aortic stenosis
  • Autograft valve function
  • Left ventricular function
  • Ross procedure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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