Clonality analysis in modern oncology and surgical pathology

Liang Cheng, Shaobo Zhang, Timothy D. Jones, Deborah E. Blue

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

CUP represents a group of biologically and clinically heterogenous tumors. Management of patients with CUP requires a truly multi-disciplinary approach and close communications between the pathologists and oncologists to ensure an effective work-up. A variety of clonality analysis methodologies can be employed to determine a site of origin for the metastatic lesion. Gene and protein expression profiling technologies are potentially of great benefit in the identification of a primary tumor and may aid in the accurate assessment of prognosis. The identification of CUP-specific molecular signatures may offer new avenues for diagnosis and treatment.

Original languageEnglish
Title of host publicationMolecular Genetic Pathology
PublisherHumana Press
Pages261-301
Number of pages41
ISBN (Print)9781588299741
DOIs
StatePublished - 2008

Fingerprint

Surgical Pathology
Gene Expression Profiling
Neoplasms
Communication
Technology
Proteins
Therapeutics
Pathologists
Oncologists

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Cheng, L., Zhang, S., Jones, T. D., & Blue, D. E. (2008). Clonality analysis in modern oncology and surgical pathology. In Molecular Genetic Pathology (pp. 261-301). Humana Press. https://doi.org/10.1007/978-1-59745-405-6_11

Clonality analysis in modern oncology and surgical pathology. / Cheng, Liang; Zhang, Shaobo; Jones, Timothy D.; Blue, Deborah E.

Molecular Genetic Pathology. Humana Press, 2008. p. 261-301.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cheng, L, Zhang, S, Jones, TD & Blue, DE 2008, Clonality analysis in modern oncology and surgical pathology. in Molecular Genetic Pathology. Humana Press, pp. 261-301. https://doi.org/10.1007/978-1-59745-405-6_11
Cheng L, Zhang S, Jones TD, Blue DE. Clonality analysis in modern oncology and surgical pathology. In Molecular Genetic Pathology. Humana Press. 2008. p. 261-301 https://doi.org/10.1007/978-1-59745-405-6_11
Cheng, Liang ; Zhang, Shaobo ; Jones, Timothy D. ; Blue, Deborah E. / Clonality analysis in modern oncology and surgical pathology. Molecular Genetic Pathology. Humana Press, 2008. pp. 261-301
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