Cloning and sequence of a chicken α-N-acetylgalactosaminidase gene

Melissa O. Davis, D. Jane Hata, Daniel Smith, John C. Walker

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

A cDNA clone encoding the mature polypeptide for the chicken liver α-N-acetylgalactosaminidase enzyme was isolated by screening a cDNA library with a synthetic sequence derived from the human α-N-acetylgalactosaminidase gene. The deduced amino acid sequence of the chicken liver clone was identical to the amino-terminal and cyanogen bromide derived peptide sequences obtained from the purified enzyme. The chicken enzyme has 75% identity with the human α-N-acetylgalactosaminidase and 56-33% identity with α-galactosidases from several sources.

Original languageEnglish (US)
Pages (from-to)296-298
Number of pages3
JournalBBA - Gene Structure and Expression
Volume1216
Issue number2
DOIs
StatePublished - Nov 16 1993
Externally publishedYes

Keywords

  • (Chicken)
  • ABO blood group system
  • Exoglycosidase
  • Gene sequencing
  • cDNA cloning

ASJC Scopus subject areas

  • Structural Biology
  • Biophysics
  • Biochemistry
  • Genetics

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