Coexistence of metastatic neuroendocrine carcinoma of the uterine cervix with human immunodeficiency virus infection

J. Balega, T. M. Ulbright, K. Y. Look

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Women now constitute 28% of new cases of human immunodeficiency virus (HIV) infection. Cervical cancer in HIV-infected women has a high recurrence and death rate, as well as decreased intervals to recurrence and death. Neuroendocrine carcinomas of the cervix are characterized by a high frequency of early nodal and distant metastases. We present the first report of a neuroendocrine carcinoma of the cervix in an HIV-positive patient. A 28 year old with a 9-year history of HIV succumbed to metastatic neuroendocrine carcinoma of the cervix 5 months after diagnosis. Given the aggressive nature of the cell type, an extended metastatic workup should be considered prior to surgery. The immune suppression present in HIV-positive patients with neuroendocrine cervical carcinoma may make such a workup particularly crucial, such that surgery is offered only to those who can be expected to benefit.

Original languageEnglish (US)
Pages (from-to)334-337
Number of pages4
JournalInternational Journal of Gynecological Cancer
Volume11
Issue number4
DOIs
StatePublished - Aug 27 2001

Keywords

  • HIV
  • Neuroendocrine cervix cancer

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Oncology
  • Cancer Research

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