Cognitive dysfunction in multiple sclerosis. II. Impact on employment and social functioning

S. M. Rao, G. J. Leo, L. Ellington, T. Nauertz, L. Bernardin, Frederick Unverzagt

Research output: Contribution to journalArticle

689 Citations (Scopus)

Abstract

We designed a study to assess the specific contribution of cognitive dysfunction to multiple sclerosis patients' problems in daily living. Based on the results of a comprehensive neuropsychological test battery, we classified 100 MS patients as either cognitively intact (N = 52) or cognitively impaired (N = 48). In addition to a neurologic examination, MS patients completed questionnaires on mood and social functioning, underwent a comprehensive in-home occupational therapy evaluation, and were rated by a close relative or friend regarding specific personality characteristics. While there were no significant differences between the two groups on measures of physical disability and illness duration, patients in the cognitively impaired group were less likely to be working, engaged in fewer social and avocational activities, reported more sexual dysfunction, experienced greater difficulty in performing routine household tasks, and exhibited more psychopathology than cognitively intact patients. These findings suggest that cognitive dysfunction is a major factor in determining the quality of life of patients with MS.

Original languageEnglish (US)
Pages (from-to)692-696
Number of pages5
JournalNeurology
Volume41
Issue number5
StatePublished - May 1991
Externally publishedYes

Fingerprint

Multiple Sclerosis
Neuropsychological Tests
Occupational Therapy
Neurologic Examination
Psychopathology
Personality
Cognitive Dysfunction
Quality of Life

ASJC Scopus subject areas

  • Neuroscience(all)
  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

Cite this

Rao, S. M., Leo, G. J., Ellington, L., Nauertz, T., Bernardin, L., & Unverzagt, F. (1991). Cognitive dysfunction in multiple sclerosis. II. Impact on employment and social functioning. Neurology, 41(5), 692-696.

Cognitive dysfunction in multiple sclerosis. II. Impact on employment and social functioning. / Rao, S. M.; Leo, G. J.; Ellington, L.; Nauertz, T.; Bernardin, L.; Unverzagt, Frederick.

In: Neurology, Vol. 41, No. 5, 05.1991, p. 692-696.

Research output: Contribution to journalArticle

Rao, SM, Leo, GJ, Ellington, L, Nauertz, T, Bernardin, L & Unverzagt, F 1991, 'Cognitive dysfunction in multiple sclerosis. II. Impact on employment and social functioning', Neurology, vol. 41, no. 5, pp. 692-696.
Rao SM, Leo GJ, Ellington L, Nauertz T, Bernardin L, Unverzagt F. Cognitive dysfunction in multiple sclerosis. II. Impact on employment and social functioning. Neurology. 1991 May;41(5):692-696.
Rao, S. M. ; Leo, G. J. ; Ellington, L. ; Nauertz, T. ; Bernardin, L. ; Unverzagt, Frederick. / Cognitive dysfunction in multiple sclerosis. II. Impact on employment and social functioning. In: Neurology. 1991 ; Vol. 41, No. 5. pp. 692-696.
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