Collagen scaffolds: Tissue engineering and repair

Eman Allam, Marco C. Bottino, Nouf Al-Shibani, L. Jack Windsor

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Tissue engineering is an emerging field that includes the development of structures that replace, repair, and maintain tissue functions. Tissue engineering is an attractive and cost-effective strategy when compared to conventional or surgical therapies. The technique involves in vitro seeding and attachment of human cells onto a scaffold. These cells then proliferate, migrate, and differentiate, as well as secrete extracellular matrix components in order to form and repair tissues. The type of scaffold and its components are therefore crucial for controlling the behavior of the cells and for the success of the therapy. Among the many scaffold materials that have been developed, the collagen-based scaffolds offer many advantageous features, as well as some limitations. The aim of this chapter is to describe the use of collagen-based scaffolds in tissue engineering and repair.

Original languageEnglish (US)
Title of host publicationType I Collagen
Subtitle of host publicationBiological Functions, Synthesis and Medicinal Applications
PublisherNova Science Publishers, Inc.
Pages145-157
Number of pages13
ISBN (Print)9781622576258
StatePublished - Nov 1 2012

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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    Allam, E., Bottino, M. C., Al-Shibani, N., & Jack Windsor, L. (2012). Collagen scaffolds: Tissue engineering and repair. In Type I Collagen: Biological Functions, Synthesis and Medicinal Applications (pp. 145-157). Nova Science Publishers, Inc..