Combination chemotherapy for disseminated malignant melanoma with DTIC, vincristine, and methyl CCNU

L. Einhorn, B. Furnas

Research output: Contribution to journalArticle

13 Scopus citations


Thirty patients with disseminated melanoma were treated with DTIC (250 mg/m2 for 5 consecutive days every 3 wk), methyl-CCNU (175 mg/m2 orally every 6 wk), and vincristine (1.4 mg/m2 weekly x 6 and then every 3 wk). Seven patients died within 3 wk of the start of chemotherapy. There was a 30% response rate (7 partial and two complete remissions) for all patients and a 39% response for evaluable patients. The median survival was 45 and 18 wk respectively for responders versus non-responders and 22 wk for all evaluable patients.

Original languageEnglish (US)
Pages (from-to)881-883
Number of pages3
JournalCancer Treatment Reports
Issue number5
StatePublished - Dec 1 1977


ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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