Thirty patients with disseminated melanoma were treated with DTIC (250 mg/m2 for 5 consecutive days every 3 wk), methyl-CCNU (175 mg/m2 orally every 6 wk), and vincristine (1.4 mg/m2 weekly x 6 and then every 3 wk). Seven patients died within 3 wk of the start of chemotherapy. There was a 30% response rate (7 partial and two complete remissions) for all patients and a 39% response for evaluable patients. The median survival was 45 and 18 wk respectively for responders versus non-responders and 22 wk for all evaluable patients.
|Original language||English (US)|
|Number of pages||3|
|Journal||Cancer Treatment Reports|
|State||Published - Dec 1 1977|
ASJC Scopus subject areas
- Cancer Research