Combination chemotherapy with CCNU (NSC 79037) and 5 [3,3 bis (2 chloroethyl) 1 thiazeno] imidazole 4 carboxamide (NSC 82196)

H. Y. Chang, E. J. Freireich, A. Khaliq, L. Einhorn, J. A. Gottlieb

Research output: Contribution to journalArticle


The authors designed a study to determine the efficacy and toxicity of combination treatment with CCNU and NSC 82196 (5-[3,3 Bis(2 chloroethyl) 1 triazeno]imidazole 4 carboxamide) in patients with advanced (predominantly refractory) solid tumors, especially adeno carcinomas. Twenty three patients, 12 men and 11 women ranging in age from 17 to 76 years with a median age of 52, with a variety of disseminated solid tumors were treated.

Original languageEnglish (US)
Pages (from-to)769-771
Number of pages3
Issue number4
StatePublished - Dec 1 1975


ASJC Scopus subject areas

  • Medicine(all)

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