Combined endosonography and fine-needle aspiration cytology in the evaluation of gastrointestinal lesions

Maurits J. Wiersema, Lisa M. Wiersema, Qazi Khusro, Harvey M. Cramer, Liang Che Tao

Research output: Contribution to journalArticle

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Abstract

Fifty consecutive patients with extrinsic or submucosal masses, gastric ulcers, or surgical anastomoses suspected of malignancy but with previously negative findings on conventional forceps biopsy or brush cytology underwent endoscopic ultrasonography followed by fine-needle aspiration cytology. Diagnostic cytology results were obtained in 37 of 50 (74%) patients. In 11 of the 13 patients with negative fine-needle aspirates, the endosonographic findings supported the final diagnosis as assessed by clinical follow-up or surgical pathology findings. In all patients, endosonography was useful for identifying the extent of the lesion and detailing regional anatomy to permit an assessment of the safest and most appropriate site for needle biopsy. The highest yield was found in evaluating tumors extrinsic to the gastrointestinal tract that were impinging on the lumen (14 of 15 or 93%). In 14 patients who underwent subsequent surgical therapy, the accuracy of fine- needle aspiration cytology was 86% (12 of 14). No complications occurred in any of the patients. EUS combined with fine-needle aspiration cytology appears to be useful in the evaluation of extrinsic or submucosal masses and suspicious appearing ulcerative lesions and surgical anastomoses of the gastrointestinal tract when conventional biopsy and brush cytology techniques have been unsuccessful.

Original languageEnglish (US)
Pages (from-to)199-206
Number of pages8
JournalGastrointestinal endoscopy
Volume40
Issue number2
DOIs
StatePublished - Jan 1 1994

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Endosonography
Fine Needle Biopsy
Cell Biology
Surgical Anastomosis
Gastrointestinal Tract
Regional Anatomy
Biopsy
Surgical Pathology
Needle Biopsy
Stomach Ulcer
Surgical Instruments
Needles
Neoplasms

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology

Cite this

Combined endosonography and fine-needle aspiration cytology in the evaluation of gastrointestinal lesions. / Wiersema, Maurits J.; Wiersema, Lisa M.; Khusro, Qazi; Cramer, Harvey M.; Tao, Liang Che.

In: Gastrointestinal endoscopy, Vol. 40, No. 2, 01.01.1994, p. 199-206.

Research output: Contribution to journalArticle

Wiersema, Maurits J. ; Wiersema, Lisa M. ; Khusro, Qazi ; Cramer, Harvey M. ; Tao, Liang Che. / Combined endosonography and fine-needle aspiration cytology in the evaluation of gastrointestinal lesions. In: Gastrointestinal endoscopy. 1994 ; Vol. 40, No. 2. pp. 199-206.
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