Comparison of computer-assisted brush biopsy results with follow up scalpel biopsy and histology.

John A. Svirsky, James C. Burns, William M. Carpenter, Donald M. Cohen, Indraneel Bhattacharyya, John E. Fantasia, David A. Lederman, Denis P. Lynch, James J. Sciubba, Susan L. Zunt

Research output: Contribution to journalArticle

58 Scopus citations

Abstract

Oral brush biopsy results were compared with scalpel biopsy and histology to determine the positive predictive value of an abnormal brush biopsy finding. Of 243 patients with abnormal brush biopsies, 93 proved positive for dysplasia (79) or carcinoma (14) and 150 were negative for either dysplasia or carcinoma. Therefore, the positive predictive value of an abnormal brush biopsy was 38% (93/243). By using the oral brush biopsy, dentists can inform their patients that abnormal findings have a strong positive predictive value for dysplasia or carcinoma and therefore require follow-up confirmation by scalpel biopsy.

Original languageEnglish (US)
Pages (from-to)500-503
Number of pages4
JournalGeneral dentistry
Volume50
Issue number6
StatePublished - Jan 1 2002
Externally publishedYes

ASJC Scopus subject areas

  • Dentistry(all)

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    Svirsky, J. A., Burns, J. C., Carpenter, W. M., Cohen, D. M., Bhattacharyya, I., Fantasia, J. E., Lederman, D. A., Lynch, D. P., Sciubba, J. J., & Zunt, S. L. (2002). Comparison of computer-assisted brush biopsy results with follow up scalpel biopsy and histology. General dentistry, 50(6), 500-503.