Factional forces between archwires and brackets play a significant role in the efficiency of orthodontic tooth movement. The objectives of this investigation were to (1) compare the wet static frictional forces of low friction "Colors" TMA™ archwires with archwires of other materials (stainless steel, NiTi, and uncoated TMA™) and (2) test the effects of repetitive sliding. A synthetic saliva solution was used to simulate the oral environment. Tested six wires were stainless steel, NiTi, TMA™, and three types of "Colors" TMA™ wires (purple, aqua and honeydew). For each said wire type, 15 archwires were tested (n=15). Each archwire type was run five times at three different weights (normal forces) and each wire was subjected to five repetitions. The effects of wire type (6 types), normal force (1267g, 2153g, 2533g) and repetition (5 per wire) on wet static frictional were examined using three-way analysis of variance (ANOVA). Pairwise comparisons between treatment combinations were made using Sidak method to control the overall significance level. The results indicated uncoated TMA™ wires produced the highest wet static frictional forces. In general, NiTi produced the next highest force levels followed by the three "Colors" TMA™ wires, and then stainless steel. Repetition was observed to affect only NiTi and uncoated TMA™ wires. NiTi wires showed a decrease in force values between runs 1 and 5 at p < 0.05. Uncoated TMA™ showed an increase in force values between runs 1 and 2.