Comparison of MAO, D β H, and COMT activities in chronic schizophrenics selected on the basis of nailfold capillary pattern

S. R. Dunlop, A. Sattin, P. Shea, H. C. Hendrie

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

A group of 17 white male chronic schizophrenic subjects were divided on the basis of plexus visualization score (PVS). High and low PVS subjects were compared to each other and to low PVS controls on measures of platelet monoamine oxidase (MAO), rbc catechol-o-methyl transferase (COMT), and plasma dopamine-β-hydroxylase (DβH). There were no differences between high and low PVS subjects on any biochemical variable. Schizophrenic subjects had lower platelet MAO activity than controls. Platelet MAO and rbc COMT were significantly correlated in schizophrenic subjects.

Original languageEnglish (US)
Pages (from-to)409-414
Number of pages6
JournalActa Psychiatrica Scandinavica
Volume64
Issue number5
DOIs
StatePublished - Nov 1981

Keywords

  • Schizophrenia
  • capillary plexus
  • catechol‐o‐methyl transferase
  • dopamine‐β‐hydroxylase
  • monoamine oxidase

ASJC Scopus subject areas

  • Psychiatry and Mental health

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