Comparison of ocular hemodynamics measured by a new retinal blood flowmeter and color doppler imaging

Larry Kagemann, Alon Harris, Christian Jonescu-Cuypers, Rishi Kumar, Clinton Sheets, Ehud Rechtman, Renata Migliardi, Hanna J. Garzozi

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

BACKGROUND AND OBJECTIVE: To compare measurements of a new retinal blood flow device with central retinal artery blood velocity. MATERIALS AND METHODS: One randomly selected eye from each of 13 subjects was examined. Blood flow was measured by laser blood flowmeter and velocity by color Doppler imaging. The correlation between measurements was analyzed using regression analysis where a P value of less than .05 and coefficient of regression values of greater than .5 were considered significant. RESULTS: The laser blood flowmeter produced vessel diameter measurements of 90.1 ± 18.7 μm (mean ± standard deviation), velocity of 19.7 ± 8.06 mm/sec, and flow measurements of 4.24 ± 2.41 μL/min. Central retinal artery peak systolic velocity, end diastolic velocity, and mean velocity correlated significantly with laser blood flowmeter velocity (P = .01, r = .66; P < .01, r = .77; and P = .003, r = .76, respectively) and flow (P = .01, r = .71; P = .03, r = .6; and P = .01, r = .69, respectively). CONCLUSIONS: The laser blood flowmeter produces retinal artery flow and velocity measurements that correlate with central retinal artery peak systolic velocity, end diastolic velocity, and mean velocity measurements. Further validation of the laser blood flowmeter's accuracy in measuring real flow is warranted and likely requires more invasive in vivo studies (in animal models). However, this study supports the ability of the laser blood flowmeter to measure retinal blood flow.

Original languageEnglish
Pages (from-to)342-347
Number of pages6
JournalOphthalmic Surgery Lasers and Imaging
Volume34
Issue number4
StatePublished - Jul 2003

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Flowmeters
Color
Hemodynamics
Retinal Artery
Lasers
Animal Models
Regression Analysis

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Kagemann, L., Harris, A., Jonescu-Cuypers, C., Kumar, R., Sheets, C., Rechtman, E., ... Garzozi, H. J. (2003). Comparison of ocular hemodynamics measured by a new retinal blood flowmeter and color doppler imaging. Ophthalmic Surgery Lasers and Imaging, 34(4), 342-347.

Comparison of ocular hemodynamics measured by a new retinal blood flowmeter and color doppler imaging. / Kagemann, Larry; Harris, Alon; Jonescu-Cuypers, Christian; Kumar, Rishi; Sheets, Clinton; Rechtman, Ehud; Migliardi, Renata; Garzozi, Hanna J.

In: Ophthalmic Surgery Lasers and Imaging, Vol. 34, No. 4, 07.2003, p. 342-347.

Research output: Contribution to journalArticle

Kagemann, L, Harris, A, Jonescu-Cuypers, C, Kumar, R, Sheets, C, Rechtman, E, Migliardi, R & Garzozi, HJ 2003, 'Comparison of ocular hemodynamics measured by a new retinal blood flowmeter and color doppler imaging', Ophthalmic Surgery Lasers and Imaging, vol. 34, no. 4, pp. 342-347.
Kagemann, Larry ; Harris, Alon ; Jonescu-Cuypers, Christian ; Kumar, Rishi ; Sheets, Clinton ; Rechtman, Ehud ; Migliardi, Renata ; Garzozi, Hanna J. / Comparison of ocular hemodynamics measured by a new retinal blood flowmeter and color doppler imaging. In: Ophthalmic Surgery Lasers and Imaging. 2003 ; Vol. 34, No. 4. pp. 342-347.
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