Comparison of Scalp Electroencephalogram with Subdural Electrocorticogram Recordings and Functional Mapping in Frontal Lobe Epilepsy

Vicenta Salanova, Harold H. Morris, Paul C. Van Ness, Hans Lüders, Dudley Dinner, Elaine Wyllie

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

We compared the findings of scalp electroencephalogram with subdural electrode array (SEA) recordings in 19 patients with refractory frontal lobe epilepsy. Prolonged scalp interictal recordings localized the epileptogenic zone in 12 patients; seven had no interictal sharp waves. The SEAs showed multifocal interictal sharp waves in all patients. Seven patients with localized seizure onset on scalp recording showed extensive ictal onset on the SEA recording. Five patients with lateralized seizure onset to one hemisphere on scalp recording were found to have ictal onset on SEA restricted to a smaller area. Because of the large epileptogenic zone found on SEA recordings, a complete resection was possible in only five (33%) of the 15 patients who had resections. Eight (53%) of the 15 patients benefited from surgery (mean follow-up, 4.6 years). The SEAs also allowed functional localization in most patients. From these data, we suggest that a localizing scalp electroencephalogram in patients with frontal lobe epilepsy may be misleading because SEA recordings show larger epileptogenic zones than anticipated. Furthermore, we postulate that the larger extensive epileptogenic zone may account for the poorer surgical outcome in patients with frontal lobe epilepsy compared with patients with temporal lobe epilepsy.

Original languageEnglish
Pages (from-to)294-299
Number of pages6
JournalArchives of Neurology
Volume50
Issue number3
DOIs
StatePublished - 1993

Fingerprint

Frontal Lobe Epilepsy
Scalp
Electroencephalography
Electrodes
Seizures
Frontal Lobe
Epilepsy
Electroencephalogram
Stroke
Temporal Lobe Epilepsy

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Comparison of Scalp Electroencephalogram with Subdural Electrocorticogram Recordings and Functional Mapping in Frontal Lobe Epilepsy. / Salanova, Vicenta; Morris, Harold H.; Van Ness, Paul C.; Lüders, Hans; Dinner, Dudley; Wyllie, Elaine.

In: Archives of Neurology, Vol. 50, No. 3, 1993, p. 294-299.

Research output: Contribution to journalArticle

Salanova, Vicenta ; Morris, Harold H. ; Van Ness, Paul C. ; Lüders, Hans ; Dinner, Dudley ; Wyllie, Elaine. / Comparison of Scalp Electroencephalogram with Subdural Electrocorticogram Recordings and Functional Mapping in Frontal Lobe Epilepsy. In: Archives of Neurology. 1993 ; Vol. 50, No. 3. pp. 294-299.
@article{8444d76b8b6c4447bbcc56a83a640f4d,
title = "Comparison of Scalp Electroencephalogram with Subdural Electrocorticogram Recordings and Functional Mapping in Frontal Lobe Epilepsy",
abstract = "We compared the findings of scalp electroencephalogram with subdural electrode array (SEA) recordings in 19 patients with refractory frontal lobe epilepsy. Prolonged scalp interictal recordings localized the epileptogenic zone in 12 patients; seven had no interictal sharp waves. The SEAs showed multifocal interictal sharp waves in all patients. Seven patients with localized seizure onset on scalp recording showed extensive ictal onset on the SEA recording. Five patients with lateralized seizure onset to one hemisphere on scalp recording were found to have ictal onset on SEA restricted to a smaller area. Because of the large epileptogenic zone found on SEA recordings, a complete resection was possible in only five (33{\%}) of the 15 patients who had resections. Eight (53{\%}) of the 15 patients benefited from surgery (mean follow-up, 4.6 years). The SEAs also allowed functional localization in most patients. From these data, we suggest that a localizing scalp electroencephalogram in patients with frontal lobe epilepsy may be misleading because SEA recordings show larger epileptogenic zones than anticipated. Furthermore, we postulate that the larger extensive epileptogenic zone may account for the poorer surgical outcome in patients with frontal lobe epilepsy compared with patients with temporal lobe epilepsy.",
author = "Vicenta Salanova and Morris, {Harold H.} and {Van Ness}, {Paul C.} and Hans L{\"u}ders and Dudley Dinner and Elaine Wyllie",
year = "1993",
doi = "10.1001/archneur.1993.00540030058015",
language = "English",
volume = "50",
pages = "294--299",
journal = "Archives of Neurology",
issn = "0003-9942",
publisher = "American Medical Association",
number = "3",

}

TY - JOUR

T1 - Comparison of Scalp Electroencephalogram with Subdural Electrocorticogram Recordings and Functional Mapping in Frontal Lobe Epilepsy

AU - Salanova, Vicenta

AU - Morris, Harold H.

AU - Van Ness, Paul C.

AU - Lüders, Hans

AU - Dinner, Dudley

AU - Wyllie, Elaine

PY - 1993

Y1 - 1993

N2 - We compared the findings of scalp electroencephalogram with subdural electrode array (SEA) recordings in 19 patients with refractory frontal lobe epilepsy. Prolonged scalp interictal recordings localized the epileptogenic zone in 12 patients; seven had no interictal sharp waves. The SEAs showed multifocal interictal sharp waves in all patients. Seven patients with localized seizure onset on scalp recording showed extensive ictal onset on the SEA recording. Five patients with lateralized seizure onset to one hemisphere on scalp recording were found to have ictal onset on SEA restricted to a smaller area. Because of the large epileptogenic zone found on SEA recordings, a complete resection was possible in only five (33%) of the 15 patients who had resections. Eight (53%) of the 15 patients benefited from surgery (mean follow-up, 4.6 years). The SEAs also allowed functional localization in most patients. From these data, we suggest that a localizing scalp electroencephalogram in patients with frontal lobe epilepsy may be misleading because SEA recordings show larger epileptogenic zones than anticipated. Furthermore, we postulate that the larger extensive epileptogenic zone may account for the poorer surgical outcome in patients with frontal lobe epilepsy compared with patients with temporal lobe epilepsy.

AB - We compared the findings of scalp electroencephalogram with subdural electrode array (SEA) recordings in 19 patients with refractory frontal lobe epilepsy. Prolonged scalp interictal recordings localized the epileptogenic zone in 12 patients; seven had no interictal sharp waves. The SEAs showed multifocal interictal sharp waves in all patients. Seven patients with localized seizure onset on scalp recording showed extensive ictal onset on the SEA recording. Five patients with lateralized seizure onset to one hemisphere on scalp recording were found to have ictal onset on SEA restricted to a smaller area. Because of the large epileptogenic zone found on SEA recordings, a complete resection was possible in only five (33%) of the 15 patients who had resections. Eight (53%) of the 15 patients benefited from surgery (mean follow-up, 4.6 years). The SEAs also allowed functional localization in most patients. From these data, we suggest that a localizing scalp electroencephalogram in patients with frontal lobe epilepsy may be misleading because SEA recordings show larger epileptogenic zones than anticipated. Furthermore, we postulate that the larger extensive epileptogenic zone may account for the poorer surgical outcome in patients with frontal lobe epilepsy compared with patients with temporal lobe epilepsy.

UR - http://www.scopus.com/inward/record.url?scp=0027477232&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027477232&partnerID=8YFLogxK

U2 - 10.1001/archneur.1993.00540030058015

DO - 10.1001/archneur.1993.00540030058015

M3 - Article

VL - 50

SP - 294

EP - 299

JO - Archives of Neurology

JF - Archives of Neurology

SN - 0003-9942

IS - 3

ER -