Comparison of the Vidas C. difficile GDH automated enzyme-linked fluorescence immunoassay (ELFA) with another commercial enzyme immunoassay (EIA) (Quik Chek-60), two selective media, and a PCR assay for gluD for detection of Clostridium difficile in fecal samples

K. A. Davies, C. E. Berry, K. A. Morris, R. Smith, S. Young, Thomas Davis, D. D. Fuller, R. J. Buckner, M. H. Wilcox

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Prevention and management of Clostridium difficile infection (CDI) can be improved by rapid and reliable diagnostics. The Vidas C. difficile glutamate dehydrogenase assay had performance comparable to that of the Quik Chek-60 assay (overall agreement, 95%) and a sensitivity of >93%; thus, it is suitable as the first test in two-stage algorithms for a CDI diagnosis.

Original languageEnglish (US)
Pages (from-to)1931-1934
Number of pages4
JournalJournal of Clinical Microbiology
Volume53
Issue number6
DOIs
StatePublished - Jun 1 2015

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Clostridium difficile
Immunoenzyme Techniques
Immunoassay
Clostridium Infections
Fluorescence
Polymerase Chain Reaction
Glutamate Dehydrogenase
galactitol 2-dehydrogenase

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Comparison of the Vidas C. difficile GDH automated enzyme-linked fluorescence immunoassay (ELFA) with another commercial enzyme immunoassay (EIA) (Quik Chek-60), two selective media, and a PCR assay for gluD for detection of Clostridium difficile in fecal samples. / Davies, K. A.; Berry, C. E.; Morris, K. A.; Smith, R.; Young, S.; Davis, Thomas; Fuller, D. D.; Buckner, R. J.; Wilcox, M. H.

In: Journal of Clinical Microbiology, Vol. 53, No. 6, 01.06.2015, p. 1931-1934.

Research output: Contribution to journalArticle

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