Comparison of the Vidas C. difficile GDH automated enzyme-linked fluorescence immunoassay (ELFA) with another commercial enzyme immunoassay (EIA) (Quik Chek-60), two selective media, and a PCR assay for gluD for detection of Clostridium difficile in fecal samples

K. A. Davies, C. E. Berry, K. A. Morris, R. Smith, S. Young, T. E. Davis, D. D. Fuller, R. J. Buckner, M. H. Wilcox

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Abstract

Prevention and management of Clostridium difficile infection (CDI) can be improved by rapid and reliable diagnostics. The Vidas C. difficile glutamate dehydrogenase assay had performance comparable to that of the Quik Chek-60 assay (overall agreement, 95%) and a sensitivity of >93%; thus, it is suitable as the first test in two-stage algorithms for a CDI diagnosis.

Original languageEnglish (US)
Pages (from-to)1931-1934
Number of pages4
JournalJournal of clinical microbiology
Volume53
Issue number6
DOIs
StatePublished - Jun 1 2015

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ASJC Scopus subject areas

  • Microbiology (medical)

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