Complete hydatidiform mole coexisting with a twin live fetus: Clinical course

J. A. Hurteau, L. M. Roth, J. M. Schilder, J. Sumners

Research output: Contribution to journalArticle

14 Scopus citations


A 33-year-old G4P0 white female presented for a pregnancy ultrasound at 9 weeks gestation and was found to have a complete hydatidiform mole coexisting with a live twin fetus (CHTF). The β-hCG level was 600,000 mIU/ml and the chest X ray was negative. The pregnancy was uneventfully terminated by suction curettage and oral contraceptives were prescribed. The initial β- hCG declined appropriately; however, it subsequently rose. The metastatic workup was negative and the patient was treated with weekly intramuscular methotrexate at 30 mg/m2. The hCG levels declined appropriately and then plateaued. Salvage chemotherapy with intraveuous actinomycin D at 1.25 mg/m2 every 14 days was started. The hCG level normalized after 3 cycles and the patient was free of disease at 1 year follow-up.

Original languageEnglish (US)
Pages (from-to)156-159
Number of pages4
JournalGynecologic Oncology
Issue number1
StatePublished - Jul 1997

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology

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