Complete remission in pure red cell aplasia after plasmapheresis

L. G. Freund, E. Hippe, S. Strandgaard, Louis Pelus, A. J. Erslev

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

A 17-year-old girl with a severe pure red cell aplasia (PRCA) and an appropriate elevation of erythropoietin titres was treated successfully with plasmapheresis, during which plasma was exchanged with human albumin and Ringer lactate. Before this treatment, therapeutic attempts with prednisolone, oxymetholone and infusions with fresh frozen had plasma all been without effect. Bone marrow culture studies revealed an inhibitor activity against BFU-E in the plasma, an activity which could not be demonstrated after the plasmapheresis. 22 months after the plasmapheresis the patient is still healthy without any medication. This case adds additional evidence for the presence of a pathogenetic erythroid inhibitory factor in the plasma of some patients with PRCA.

Original languageEnglish (US)
Pages (from-to)315-318
Number of pages4
JournalScandinavian Journal of Haematology
Volume35
Issue number3
StatePublished - 1985
Externally publishedYes

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Pure Red-Cell Aplasia
Plasmapheresis
Oxymetholone
Erythroid Precursor Cells
Erythropoietin
Prednisolone
Albumins
Bone Marrow
Therapeutics

ASJC Scopus subject areas

  • Hematology

Cite this

Freund, L. G., Hippe, E., Strandgaard, S., Pelus, L., & Erslev, A. J. (1985). Complete remission in pure red cell aplasia after plasmapheresis. Scandinavian Journal of Haematology, 35(3), 315-318.

Complete remission in pure red cell aplasia after plasmapheresis. / Freund, L. G.; Hippe, E.; Strandgaard, S.; Pelus, Louis; Erslev, A. J.

In: Scandinavian Journal of Haematology, Vol. 35, No. 3, 1985, p. 315-318.

Research output: Contribution to journalArticle

Freund, LG, Hippe, E, Strandgaard, S, Pelus, L & Erslev, AJ 1985, 'Complete remission in pure red cell aplasia after plasmapheresis', Scandinavian Journal of Haematology, vol. 35, no. 3, pp. 315-318.
Freund, L. G. ; Hippe, E. ; Strandgaard, S. ; Pelus, Louis ; Erslev, A. J. / Complete remission in pure red cell aplasia after plasmapheresis. In: Scandinavian Journal of Haematology. 1985 ; Vol. 35, No. 3. pp. 315-318.
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