Complete reversal of glycogen hepatopathy with pancreas transplantation: Two cases

Jonathan A. Fridell, Romil Saxena, Naga Chalasani, William C. Goggins, John A. Powelson, Oscar Cummings

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Glycogen hepatopathy is the pathological overloading of hepatocytes with glycogen that is associated with poorly controlled diabetes mellitus. Clinically, it presents with abdominal discomfort, tender hepatomegaly and elevated transaminases. In this report, we describe our experience with two cases of type I diabetes mellitus and glycogen hepatopathy. The patients underwent isolated pancreas transplantation, following which, we have been able to demonstrate complete histological resolution of glycogen hepatopathy associated with control of glucose metabolism.

Original languageEnglish
Pages (from-to)84-86
Number of pages3
JournalTransplantation
Volume83
Issue number1
DOIs
StatePublished - Jan 2007

Fingerprint

Pancreas Transplantation
Glycogen
Hepatomegaly
Transaminases
Type 1 Diabetes Mellitus
Hepatocytes
Diabetes Mellitus
Glucose

Keywords

  • Diabetes mellitus
  • Glycogen hepatopathy
  • Pancreas transplantation

ASJC Scopus subject areas

  • Transplantation
  • Immunology

Cite this

Complete reversal of glycogen hepatopathy with pancreas transplantation : Two cases. / Fridell, Jonathan A.; Saxena, Romil; Chalasani, Naga; Goggins, William C.; Powelson, John A.; Cummings, Oscar.

In: Transplantation, Vol. 83, No. 1, 01.2007, p. 84-86.

Research output: Contribution to journalArticle

Fridell, Jonathan A. ; Saxena, Romil ; Chalasani, Naga ; Goggins, William C. ; Powelson, John A. ; Cummings, Oscar. / Complete reversal of glycogen hepatopathy with pancreas transplantation : Two cases. In: Transplantation. 2007 ; Vol. 83, No. 1. pp. 84-86.
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