Complete reversal of glycogen hepatopathy with pancreas transplantation: Two cases

Jonathan A. Fridell, Romil Saxena, Naga P. Chalasani, William C. Goggins, John A. Powelson, Oscar W. Cummings

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

Glycogen hepatopathy is the pathological overloading of hepatocytes with glycogen that is associated with poorly controlled diabetes mellitus. Clinically, it presents with abdominal discomfort, tender hepatomegaly and elevated transaminases. In this report, we describe our experience with two cases of type I diabetes mellitus and glycogen hepatopathy. The patients underwent isolated pancreas transplantation, following which, we have been able to demonstrate complete histological resolution of glycogen hepatopathy associated with control of glucose metabolism.

Original languageEnglish (US)
Pages (from-to)84-86
Number of pages3
JournalTransplantation
Volume83
Issue number1
DOIs
StatePublished - Jan 1 2007

Keywords

  • Diabetes mellitus
  • Glycogen hepatopathy
  • Pancreas transplantation

ASJC Scopus subject areas

  • Transplantation
  • Immunology

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