Complications of small intestinal submucosa for corporal body grafting for proximal hypospadias

Trevor M. Soergel, Mark P. Cain, Martin Kaefer, Jordan Gitlin, Anthony J. Casale, Mary M. Davis, Richard C. Rink

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Purpose: Small intestinal submucosa (SIS) has been described for corporal body grafting in cases of severe penile curvature. We reviewed our experience with a 2-stage repair using corporal body grafting with SIS for proximal hypospadias and severe chordee. Materials and Methods. A retrospective chart review was performed on 12 patients with penoscrotal hypospadias and severe chordee. Corporal grafting was performed with a 4-layer SIS graft (STRATASIS, Cook Biotech, Spencer, Indiana). Patients were evaluated postoperatively with clinic visits after both stages of repair to assess results. Results: Corporal body grafting with SIS was performed in 12 patients between June and December 2001. Average patient age at the time of stage 1 repair was 9 months. Of the 12 patients 8 (66%) had no complications and 10 (83%) have a straight phallus following stage 2 repair. Complications occurred in 4 patients (33%), 2 of which were minor and did not require surgical correction. There were 2 major complications related to the SIS graft, 1 of which required excision of the graft and replacement with a tunica albuginea flap, and the other required 3 dorsal plications to correct residual chordee. Conclusions: Our experience using the 4-layer SIS resulted in 2 major complications requiring surgical correction during stage 2 repair. This rate exceeds the complications reported with either dermal or tunica vaginalis grafts. Currently we have stopped using SIS for corporal grafting.

Original languageEnglish (US)
Pages (from-to)1577-1578
Number of pages2
JournalJournal of Urology
Volume170
Issue number4 II
DOIs
StatePublished - Oct 1 2003
Externally publishedYes

Fingerprint

Hypospadias
Transplants
Ambulatory Care
Skin

Keywords

  • Hypospadias, graft
  • Mucosa, intestinal

ASJC Scopus subject areas

  • Urology

Cite this

Soergel, T. M., Cain, M. P., Kaefer, M., Gitlin, J., Casale, A. J., Davis, M. M., & Rink, R. C. (2003). Complications of small intestinal submucosa for corporal body grafting for proximal hypospadias. Journal of Urology, 170(4 II), 1577-1578. https://doi.org/10.1097/01.ju.0000083802.87337.af

Complications of small intestinal submucosa for corporal body grafting for proximal hypospadias. / Soergel, Trevor M.; Cain, Mark P.; Kaefer, Martin; Gitlin, Jordan; Casale, Anthony J.; Davis, Mary M.; Rink, Richard C.

In: Journal of Urology, Vol. 170, No. 4 II, 01.10.2003, p. 1577-1578.

Research output: Contribution to journalArticle

Soergel, Trevor M. ; Cain, Mark P. ; Kaefer, Martin ; Gitlin, Jordan ; Casale, Anthony J. ; Davis, Mary M. ; Rink, Richard C. / Complications of small intestinal submucosa for corporal body grafting for proximal hypospadias. In: Journal of Urology. 2003 ; Vol. 170, No. 4 II. pp. 1577-1578.
@article{3a8a9d973a58454f8c599f1105d76f81,
title = "Complications of small intestinal submucosa for corporal body grafting for proximal hypospadias",
abstract = "Purpose: Small intestinal submucosa (SIS) has been described for corporal body grafting in cases of severe penile curvature. We reviewed our experience with a 2-stage repair using corporal body grafting with SIS for proximal hypospadias and severe chordee. Materials and Methods. A retrospective chart review was performed on 12 patients with penoscrotal hypospadias and severe chordee. Corporal grafting was performed with a 4-layer SIS graft (STRATASIS, Cook Biotech, Spencer, Indiana). Patients were evaluated postoperatively with clinic visits after both stages of repair to assess results. Results: Corporal body grafting with SIS was performed in 12 patients between June and December 2001. Average patient age at the time of stage 1 repair was 9 months. Of the 12 patients 8 (66{\%}) had no complications and 10 (83{\%}) have a straight phallus following stage 2 repair. Complications occurred in 4 patients (33{\%}), 2 of which were minor and did not require surgical correction. There were 2 major complications related to the SIS graft, 1 of which required excision of the graft and replacement with a tunica albuginea flap, and the other required 3 dorsal plications to correct residual chordee. Conclusions: Our experience using the 4-layer SIS resulted in 2 major complications requiring surgical correction during stage 2 repair. This rate exceeds the complications reported with either dermal or tunica vaginalis grafts. Currently we have stopped using SIS for corporal grafting.",
keywords = "Hypospadias, graft, Mucosa, intestinal",
author = "Soergel, {Trevor M.} and Cain, {Mark P.} and Martin Kaefer and Jordan Gitlin and Casale, {Anthony J.} and Davis, {Mary M.} and Rink, {Richard C.}",
year = "2003",
month = "10",
day = "1",
doi = "10.1097/01.ju.0000083802.87337.af",
language = "English (US)",
volume = "170",
pages = "1577--1578",
journal = "Journal of Urology",
issn = "0022-5347",
publisher = "Elsevier Inc.",
number = "4 II",

}

TY - JOUR

T1 - Complications of small intestinal submucosa for corporal body grafting for proximal hypospadias

AU - Soergel, Trevor M.

AU - Cain, Mark P.

AU - Kaefer, Martin

AU - Gitlin, Jordan

AU - Casale, Anthony J.

AU - Davis, Mary M.

AU - Rink, Richard C.

PY - 2003/10/1

Y1 - 2003/10/1

N2 - Purpose: Small intestinal submucosa (SIS) has been described for corporal body grafting in cases of severe penile curvature. We reviewed our experience with a 2-stage repair using corporal body grafting with SIS for proximal hypospadias and severe chordee. Materials and Methods. A retrospective chart review was performed on 12 patients with penoscrotal hypospadias and severe chordee. Corporal grafting was performed with a 4-layer SIS graft (STRATASIS, Cook Biotech, Spencer, Indiana). Patients were evaluated postoperatively with clinic visits after both stages of repair to assess results. Results: Corporal body grafting with SIS was performed in 12 patients between June and December 2001. Average patient age at the time of stage 1 repair was 9 months. Of the 12 patients 8 (66%) had no complications and 10 (83%) have a straight phallus following stage 2 repair. Complications occurred in 4 patients (33%), 2 of which were minor and did not require surgical correction. There were 2 major complications related to the SIS graft, 1 of which required excision of the graft and replacement with a tunica albuginea flap, and the other required 3 dorsal plications to correct residual chordee. Conclusions: Our experience using the 4-layer SIS resulted in 2 major complications requiring surgical correction during stage 2 repair. This rate exceeds the complications reported with either dermal or tunica vaginalis grafts. Currently we have stopped using SIS for corporal grafting.

AB - Purpose: Small intestinal submucosa (SIS) has been described for corporal body grafting in cases of severe penile curvature. We reviewed our experience with a 2-stage repair using corporal body grafting with SIS for proximal hypospadias and severe chordee. Materials and Methods. A retrospective chart review was performed on 12 patients with penoscrotal hypospadias and severe chordee. Corporal grafting was performed with a 4-layer SIS graft (STRATASIS, Cook Biotech, Spencer, Indiana). Patients were evaluated postoperatively with clinic visits after both stages of repair to assess results. Results: Corporal body grafting with SIS was performed in 12 patients between June and December 2001. Average patient age at the time of stage 1 repair was 9 months. Of the 12 patients 8 (66%) had no complications and 10 (83%) have a straight phallus following stage 2 repair. Complications occurred in 4 patients (33%), 2 of which were minor and did not require surgical correction. There were 2 major complications related to the SIS graft, 1 of which required excision of the graft and replacement with a tunica albuginea flap, and the other required 3 dorsal plications to correct residual chordee. Conclusions: Our experience using the 4-layer SIS resulted in 2 major complications requiring surgical correction during stage 2 repair. This rate exceeds the complications reported with either dermal or tunica vaginalis grafts. Currently we have stopped using SIS for corporal grafting.

KW - Hypospadias, graft

KW - Mucosa, intestinal

UR - http://www.scopus.com/inward/record.url?scp=0041815946&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0041815946&partnerID=8YFLogxK

U2 - 10.1097/01.ju.0000083802.87337.af

DO - 10.1097/01.ju.0000083802.87337.af

M3 - Article

VL - 170

SP - 1577

EP - 1578

JO - Journal of Urology

JF - Journal of Urology

SN - 0022-5347

IS - 4 II

ER -