Composite liver tumors: a radiologic-pathologic correlation

Megha Nayyar, David K. Imagawa, Temel Tirkes, Aram N. Demirjian, Roozbeh Houshyar, Kumar Sandrasegaran, Chaitali S. Nangia, Tara Seery, P. Bhargava, Joon I.i. Choi, Chandana Lall

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Bi-phenotypic neoplasm refers to tumors derived from a common cancer stem cell with unique capability to differentiate histologically into two distinct tumor types. Bi-phenotypic hepatocellular carcinoma-cholangiocarcinoma (HCC-CC), although a rare tumor, is important for clinicians to recognize, since treatment options targeting both elements of the tumor are crucial. Imaging findings of bi-phenotypic HCC-CC are not specific and include features of both HCC and CC. A combination of imaging and immuno-histochemical analysis is usually needed to make the diagnosis.

Original languageEnglish (US)
Pages (from-to)406-410
Number of pages5
JournalClinical and molecular hepatology
Volume20
Issue number4
DOIs
StatePublished - Dec 1 2014

Keywords

  • Bi-phenotypic tumors
  • Cholangiocarcinoma
  • Computed tomography, Magnetic resonance imaging
  • Hepatoceullular carcinoma

ASJC Scopus subject areas

  • Hepatology
  • Molecular Biology

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  • Cite this

    Nayyar, M., Imagawa, D. K., Tirkes, T., Demirjian, A. N., Houshyar, R., Sandrasegaran, K., Nangia, C. S., Seery, T., Bhargava, P., Choi, J. I. I., & Lall, C. (2014). Composite liver tumors: a radiologic-pathologic correlation. Clinical and molecular hepatology, 20(4), 406-410. https://doi.org/10.3350/cmh.2014.20.4.406