Composite liver tumors

a radiologic-pathologic correlation

Megha Nayyar, David K. Imagawa, Temel Tirkes, Aram N. Demirjian, Roozbeh Houshyar, Kumar Sandrasegaran, Chaitali S. Nangia, Tara Seery, P. Bhargava, Joon I i Choi, Chandana Lall

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Bi-phenotypic neoplasm refers to tumors derived from a common cancer stem cell with unique capability to differentiate histologically into two distinct tumor types. Bi-phenotypic hepatocellular carcinoma-cholangiocarcinoma (HCC-CC), although a rare tumor, is important for clinicians to recognize, since treatment options targeting both elements of the tumor are crucial. Imaging findings of bi-phenotypic HCC-CC are not specific and include features of both HCC and CC. A combination of imaging and immuno-histochemical analysis is usually needed to make the diagnosis.

Original languageEnglish (US)
Pages (from-to)406-410
Number of pages5
JournalClinical and molecular hepatology
Volume20
Issue number4
DOIs
StatePublished - Dec 1 2014

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Liver
Cholangiocarcinoma
Neoplasms
Hepatocellular Carcinoma
Neoplastic Stem Cells

Keywords

  • Bi-phenotypic tumors
  • Cholangiocarcinoma
  • Computed tomography, Magnetic resonance imaging
  • Hepatoceullular carcinoma

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Composite liver tumors : a radiologic-pathologic correlation. / Nayyar, Megha; Imagawa, David K.; Tirkes, Temel; Demirjian, Aram N.; Houshyar, Roozbeh; Sandrasegaran, Kumar; Nangia, Chaitali S.; Seery, Tara; Bhargava, P.; Choi, Joon I i; Lall, Chandana.

In: Clinical and molecular hepatology, Vol. 20, No. 4, 01.12.2014, p. 406-410.

Research output: Contribution to journalArticle

Nayyar, M, Imagawa, DK, Tirkes, T, Demirjian, AN, Houshyar, R, Sandrasegaran, K, Nangia, CS, Seery, T, Bhargava, P, Choi, JII & Lall, C 2014, 'Composite liver tumors: a radiologic-pathologic correlation', Clinical and molecular hepatology, vol. 20, no. 4, pp. 406-410. https://doi.org/10.3350/cmh.2014.20.4.406
Nayyar, Megha ; Imagawa, David K. ; Tirkes, Temel ; Demirjian, Aram N. ; Houshyar, Roozbeh ; Sandrasegaran, Kumar ; Nangia, Chaitali S. ; Seery, Tara ; Bhargava, P. ; Choi, Joon I i ; Lall, Chandana. / Composite liver tumors : a radiologic-pathologic correlation. In: Clinical and molecular hepatology. 2014 ; Vol. 20, No. 4. pp. 406-410.
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