Computational Anatomy in Alzheimer's Disease

Alex D. Leow, Liana G. Apostolova, Paul M. Thompson

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Computational anatomy covers a broad class of mathematical methods that model anatomical structures in images as three-dimensional curves, surfaces and volumes, and combine them across subjects to create statistical maps of structural differences among brains. The methods described here are cortical thickness mapping, time-lapse, tensor-based morphometry, and hippocampal radial mapping.

Original languageEnglish (US)
Title of host publicationPrinciples and Practice of Geriatric Psychiatry
Subtitle of host publicationThird Edition
PublisherJohn Wiley and Sons
Pages262-270
Number of pages9
ISBN (Print)9780470747230
DOIs
StatePublished - Dec 2 2010

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Leow, A. D., Apostolova, L. G., & Thompson, P. M. (2010). Computational Anatomy in Alzheimer's Disease. In Principles and Practice of Geriatric Psychiatry: Third Edition (pp. 262-270). John Wiley and Sons. https://doi.org/10.1002/9780470669600.ch46