Concordance between anxiety and autonomic nervous system activity in subjects at genetic risk for affective disorder

Theodore P. Zahn, John Nurnberger, Wade H. Berrettini, Thomas N. Robinson

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Correlations between electrodermal and heart rate indices of autonomic nervous system (ANS) activity and measures of state and trait anxiety were examined in 22 high-risk subjects, who had a parent with bipolar affective disorder, and in controls. Relatively consistent and significant correlations between anxiety and ANS "arousal" at rest and under stress were found in high-risk subjects, but not in controls. Relationships between electrodermal laterality and anxiety, and between electrodermal activity and heart rate, were also observed only in the high-risk group. The data suggest a unique concordance between various manifestations of anxiety in high-risk persons which may effectively increase the salience of stressful events and the sensitization to stress.

Original languageEnglish
Pages (from-to)99-110
Number of pages12
JournalPsychiatry Research
Volume36
Issue number1
DOIs
StatePublished - 1991
Externally publishedYes

Fingerprint

Autonomic Nervous System
Mood Disorders
Anxiety
Heart Rate
Arousal
Bipolar Disorder

Keywords

  • Affective disorder
  • electrodermal activity
  • heart rate
  • high risk
  • stress
  • vulnerability

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry
  • Psychology(all)

Cite this

Concordance between anxiety and autonomic nervous system activity in subjects at genetic risk for affective disorder. / Zahn, Theodore P.; Nurnberger, John; Berrettini, Wade H.; Robinson, Thomas N.

In: Psychiatry Research, Vol. 36, No. 1, 1991, p. 99-110.

Research output: Contribution to journalArticle

Zahn, Theodore P. ; Nurnberger, John ; Berrettini, Wade H. ; Robinson, Thomas N. / Concordance between anxiety and autonomic nervous system activity in subjects at genetic risk for affective disorder. In: Psychiatry Research. 1991 ; Vol. 36, No. 1. pp. 99-110.
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