Contrast-enhanced magnetization transfer saturation imaging improves MR detection of herpes simplex encephalitis

Jerry W. Burke, Vincent P. Mathews, Allen D. Elster, John L. Ulmer, Frederick M. McLean, Steven B. Davis

Research output: Contribution to journalArticle

32 Scopus citations


Cranial MR imaging was performed in three patients in whom herpes simplex encephalitis was subsequently proved. In all cases, the postcontrast T1- weighted MR images obtained with magnetization transfer saturation showed greater central nervous system involvement than was apparent on the conventional MR images. Specifically, the postcontrast magnetization transfer images were superior at delineating generalized meningeal enhancement as well as focal areas of brain involvement not seen on noncontrast T2-weighted images or conventional postcontrast T1-weighted images.

Original languageEnglish (US)
Pages (from-to)773-776
Number of pages4
JournalAmerican Journal of Neuroradiology
Issue number4
StatePublished - Apr 1 1996



  • Encephalitis
  • Herpes simplex
  • Magnetic resonance, magnetization transfer

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

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