Correction of motion artifact in cardiac optical mapping using image registration technique

Gustavo K. Rohde, Veniamin Sidorov, Akram Aldroubi, Benoit M. Dawant, Shien Fong Lin

Research output: Contribution to journalConference article

2 Scopus citations


Myocardial contraction causes motion artifact in cardiac optical recording. Mechanical and chemical methods have been used, both with significant limitations, to reduce motion artifact in optical mapping. We propose an image registration approach using mutual information between image frames to solve this problem. The algorithm was tested with optical mapping data from isolated, perfused rabbit hearts. Both affine and nonrigid registration methods reduced motion artifact as measured by a reduction in excessive positive and negative deflection in the optical potential traces after the registration process. Such an approach could be further developed for real-time, in vivo electrophysiological measurement.

Original languageEnglish (US)
Pages (from-to)1375-1376
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
StatePublished - Dec 1 2002
Externally publishedYes
EventProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States
Duration: Oct 23 2002Oct 26 2002


  • Heart
  • Image registration
  • Optical mapping

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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